Araloside C Prevents Hypoxia/Reoxygenation-Induced Endoplasmic Reticulum Stress via Increasing Heat Shock Protein 90 in H9c2 Cardiomyocytes

Araloside C Prevents Hypoxia/Reoxygenation-Induced Endoplasmic Reticulum Stress via Increasing Heat Shock Protein 90 in H9c2 Cardiomyocytes

Araloside C (AsC) is a cardioprotective triterpenoid compound that is mainly isolated from Aralia elata. This study aims to determine the effects of AsC on hypoxia-reoxygenation (H/R)-induced apoptosis in H9c2 cardiomyocytes and its underlying mechanisms. Results demonstrated that pretreatment with...

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Bibliographic Details
Main Authors: Yuyang Du, Min Wang, Xuesong Liu, Jingyi Zhang, Xudong Xu, Huibo Xu, Guibo Sun, Xiaobo Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Pharmacology
Subjects:
Araloside C
hypoxia/reoxygenation injury
endoplasmic reticulum stress
heat shock protein 90
apoptosis
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00180/full

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