WLS-Wnt signaling promotes neuroendocrine prostate cancer

WLS-Wnt signaling promotes neuroendocrine prostate cancer

Summary: Neuroendocrine prostate cancer (NEPC) is a lethal prostate cancer subtype arising as a consequence of more potent androgen receptor (AR) targeting in castration-resistant prostate cancer (CRPC). Its molecular pathogenesis remains elusive. Here, we report that the Wnt secretion mediator Wntl...

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Bibliographic Details
Main Authors: Tyler Bland, Jing Wang, Lijuan Yin, Tianjie Pu, Jingjing Li, Jin Gao, Tzu-Ping Lin, Allen C. Gao, Boyang Jason Wu
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Biological Sciences
Cell Biology
Cancer
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220311676

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