Myeloid sarcoma of uterine cervix: A case report with review of the literature
Myeloid sarcoma is a rare clinical entity, characterised by the extramedullary presence of myeloblasts. It can occur de novo or signify disease recurrence. Involvement of the female reproductive tract is uncommon, with most cases involving the uterine corpus or ovary. Patients with non-leukaemic mye...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-02-01
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| Series: | Gynecologic Oncology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S235257892200011X |
| _version_ | 1818320172028526592 |
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| author | C. Mullen S. Beverstock H. Roddie V.L. Campbell W. Al-Qsous |
| author_facet | C. Mullen S. Beverstock H. Roddie V.L. Campbell W. Al-Qsous |
| author_sort | C. Mullen |
| collection | DOAJ |
| description | Myeloid sarcoma is a rare clinical entity, characterised by the extramedullary presence of myeloblasts. It can occur de novo or signify disease recurrence. Involvement of the female reproductive tract is uncommon, with most cases involving the uterine corpus or ovary. Patients with non-leukaemic myeloid sarcoma are treated with acute myeloid leukaemia (AML) regimens, but the optimal therapy is unclear due to the relative rarity of the condition and lack of clinical trial data. We present an unusual case of myeloid sarcoma of the uterine cervix diagnosed incidentally in a patient with cervical-intraepithelial neoplasia grade 2 (CIN2), followed by a literature review. |
| first_indexed | 2024-12-13T10:20:47Z |
| format | Article |
| id | doaj.art-1d390f725701460082ca30927bd8f759 |
| institution | Directory Open Access Journal |
| issn | 2352-5789 |
| language | English |
| last_indexed | 2024-12-13T10:20:47Z |
| publishDate | 2022-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Gynecologic Oncology Reports |
| spelling | doaj.art-1d390f725701460082ca30927bd8f7592022-12-21T23:51:11ZengElsevierGynecologic Oncology Reports2352-57892022-02-0139100931Myeloid sarcoma of uterine cervix: A case report with review of the literatureC. Mullen0S. Beverstock1H. Roddie2V.L. Campbell3W. Al-Qsous4Department of Haematology, Western General Hospital, Edinburgh, United KingdomDepartment of Haematology, Western General Hospital, Edinburgh, United KingdomDepartment of Haematology, Western General Hospital, Edinburgh, United KingdomDepartment of Haematology, Western General Hospital, Edinburgh, United KingdomDepartment of Pathology, Western General Hospital, Edinburgh, United Kingdom; Corresponding author at: Department of Pathology, Alexander Donald Building, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, United Kingdom.Myeloid sarcoma is a rare clinical entity, characterised by the extramedullary presence of myeloblasts. It can occur de novo or signify disease recurrence. Involvement of the female reproductive tract is uncommon, with most cases involving the uterine corpus or ovary. Patients with non-leukaemic myeloid sarcoma are treated with acute myeloid leukaemia (AML) regimens, but the optimal therapy is unclear due to the relative rarity of the condition and lack of clinical trial data. We present an unusual case of myeloid sarcoma of the uterine cervix diagnosed incidentally in a patient with cervical-intraepithelial neoplasia grade 2 (CIN2), followed by a literature review.http://www.sciencedirect.com/science/article/pii/S235257892200011XMyeloid sarcomaUterine cervixAcute myeloid leukaemia |
| spellingShingle | C. Mullen S. Beverstock H. Roddie V.L. Campbell W. Al-Qsous Myeloid sarcoma of uterine cervix: A case report with review of the literature Gynecologic Oncology Reports Myeloid sarcoma Uterine cervix Acute myeloid leukaemia |
| title | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
| title_full | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
| title_fullStr | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
| title_full_unstemmed | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
| title_short | Myeloid sarcoma of uterine cervix: A case report with review of the literature |
| title_sort | myeloid sarcoma of uterine cervix a case report with review of the literature |
| topic | Myeloid sarcoma Uterine cervix Acute myeloid leukaemia |
| url | http://www.sciencedirect.com/science/article/pii/S235257892200011X |
| work_keys_str_mv | AT cmullen myeloidsarcomaofuterinecervixacasereportwithreviewoftheliterature AT sbeverstock myeloidsarcomaofuterinecervixacasereportwithreviewoftheliterature AT hroddie myeloidsarcomaofuterinecervixacasereportwithreviewoftheliterature AT vlcampbell myeloidsarcomaofuterinecervixacasereportwithreviewoftheliterature AT walqsous myeloidsarcomaofuterinecervixacasereportwithreviewoftheliterature |