High Resolution Computed Tomography in Asthma
Objectives: High-resolution computed tomography (HRCT) can detect the structural abnormalities in asthma. This study attempts to correlate these abnormalities with clinical and pulmonary function test (PFT) data.Methods: Consecutive stable asthma patients attending Mubarak Al Kabeer Hospital, Kuwait...
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| Format: | Article |
| Language: | English |
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Oman Medical Specialty Board
2012-03-01
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| Series: | Oman Medical Journal |
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| Online Access: | http://journals.indexcopernicus.com/fulltxt.php?ICID=989901 |
| _version_ | 1818049553004232704 |
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| author | Nabil Maradny Tariq Sinan Omolara Roberts Abdulaziz Muquim Jayakrishnan B Mousa Khadadah Ibrahim Lasheen |
| author_facet | Nabil Maradny Tariq Sinan Omolara Roberts Abdulaziz Muquim Jayakrishnan B Mousa Khadadah Ibrahim Lasheen |
| author_sort | Nabil Maradny |
| collection | DOAJ |
| description | Objectives: High-resolution computed tomography (HRCT) can detect the structural abnormalities in asthma. This study attempts to correlate these abnormalities with clinical and pulmonary function test (PFT) data.Methods: Consecutive stable asthma patients attending Mubarak Al Kabeer Hospital, Kuwait, were subjected to HRCT during a six month period from July 2004 to December 2004, after initial evaluation and PFT.Results: Of the 28 cases, sixteen (57.1�20had moderate, 6 (21.4�20had mild and 6 (21.4�20had severe persistent asthma. Thirteen (46.4�20patients had asthma for 1 to 5 years and 12 (42.9�20were having asthma for >10 years. Bronchial wall thickening (57.1� bronchiectasis (28.6� mucoid impaction (17.9� mosaic attenuation (10.7� air trapping (78.6�20and plate like atelectasis (21.4�20were noted. Bronchial wall thickening (p=0.044) and bronchiectasis (p=0.063) were most prevalent in males. Ten (35.7�20patients exhibited mild, 9 (32.1�20had moderate and 3 (10.7�20had severe air trapping. The difference in Hounsfield units between expiratory and inspiratory slices (air trapping) when correlated with percent-predicted FEV1 in right upper (r=0.25;p=0.30), left upper (r=0.20; p=0.41), right mid (r=0.15; p=0.53), left mid (r=-0.04; p=0.60), right lower (r=0.04; p=0.86) and left lower zones (r=-0.13; p=0.58) showed no relation. The same when correlated as above with the percent predicted FEF 25-75 did not show any significant association. The presence of air trapping was compared with sex (p=0.640), nationality (p=1.000), disease duration (p=1.000) and severity of symptoms (p=0.581).Conclusion: Abnormal HRCT findings are common in asthma; however, air trapping when present was not related to the duration or severity of the illness or to the FEV1. |
| first_indexed | 2024-12-10T10:39:24Z |
| format | Article |
| id | doaj.art-1d395cacf10b4d8a9eae6ff20cf8afe5 |
| institution | Directory Open Access Journal |
| issn | 1999-768X 2070-5204 |
| language | English |
| last_indexed | 2024-12-10T10:39:24Z |
| publishDate | 2012-03-01 |
| publisher | Oman Medical Specialty Board |
| record_format | Article |
| series | Oman Medical Journal |
| spelling | doaj.art-1d395cacf10b4d8a9eae6ff20cf8afe52022-12-22T01:52:21ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042012-03-01272145150High Resolution Computed Tomography in AsthmaNabil MaradnyTariq SinanOmolara RobertsAbdulaziz MuquimJayakrishnan BMousa KhadadahIbrahim LasheenObjectives: High-resolution computed tomography (HRCT) can detect the structural abnormalities in asthma. This study attempts to correlate these abnormalities with clinical and pulmonary function test (PFT) data.Methods: Consecutive stable asthma patients attending Mubarak Al Kabeer Hospital, Kuwait, were subjected to HRCT during a six month period from July 2004 to December 2004, after initial evaluation and PFT.Results: Of the 28 cases, sixteen (57.1�20had moderate, 6 (21.4�20had mild and 6 (21.4�20had severe persistent asthma. Thirteen (46.4�20patients had asthma for 1 to 5 years and 12 (42.9�20were having asthma for >10 years. Bronchial wall thickening (57.1� bronchiectasis (28.6� mucoid impaction (17.9� mosaic attenuation (10.7� air trapping (78.6�20and plate like atelectasis (21.4�20were noted. Bronchial wall thickening (p=0.044) and bronchiectasis (p=0.063) were most prevalent in males. Ten (35.7�20patients exhibited mild, 9 (32.1�20had moderate and 3 (10.7�20had severe air trapping. The difference in Hounsfield units between expiratory and inspiratory slices (air trapping) when correlated with percent-predicted FEV1 in right upper (r=0.25;p=0.30), left upper (r=0.20; p=0.41), right mid (r=0.15; p=0.53), left mid (r=-0.04; p=0.60), right lower (r=0.04; p=0.86) and left lower zones (r=-0.13; p=0.58) showed no relation. The same when correlated as above with the percent predicted FEF 25-75 did not show any significant association. The presence of air trapping was compared with sex (p=0.640), nationality (p=1.000), disease duration (p=1.000) and severity of symptoms (p=0.581).Conclusion: Abnormal HRCT findings are common in asthma; however, air trapping when present was not related to the duration or severity of the illness or to the FEV1.http://journals.indexcopernicus.com/fulltxt.php?ICID=989901Asthmacomputed tomographyHRCTpulmonary functionair trappingBronchiectasis |
| spellingShingle | Nabil Maradny Tariq Sinan Omolara Roberts Abdulaziz Muquim Jayakrishnan B Mousa Khadadah Ibrahim Lasheen High Resolution Computed Tomography in Asthma Oman Medical Journal Asthma computed tomography HRCT pulmonary function air trapping Bronchiectasis |
| title | High Resolution Computed Tomography in Asthma |
| title_full | High Resolution Computed Tomography in Asthma |
| title_fullStr | High Resolution Computed Tomography in Asthma |
| title_full_unstemmed | High Resolution Computed Tomography in Asthma |
| title_short | High Resolution Computed Tomography in Asthma |
| title_sort | high resolution computed tomography in asthma |
| topic | Asthma computed tomography HRCT pulmonary function air trapping Bronchiectasis |
| url | http://journals.indexcopernicus.com/fulltxt.php?ICID=989901 |
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