A New Cure Rate Model Based on Flory–Schulz Distribution: Application to the Cancer Data

In this article a new flexible survival cure rate model is introduced by assuming that the number of competing causes of the event of interest follows the Flory–Schulz distribution and the competing causes follow the generalized truncated Nadarajah–Haghighi distribution. Parameter estimation for the...

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Main Authors: Reza Azimi, Mahdy Esmailian, Diego I. Gallardo, Héctor J. Gómez
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Mathematics
Subjects:
Online Access:https://www.mdpi.com/2227-7390/10/24/4643
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author Reza Azimi
Mahdy Esmailian
Diego I. Gallardo
Héctor J. Gómez
author_facet Reza Azimi
Mahdy Esmailian
Diego I. Gallardo
Héctor J. Gómez
author_sort Reza Azimi
collection DOAJ
description In this article a new flexible survival cure rate model is introduced by assuming that the number of competing causes of the event of interest follows the Flory–Schulz distribution and the competing causes follow the generalized truncated Nadarajah–Haghighi distribution. Parameter estimation for the proposed model is derived based on the maximum likelihood estimation method. A simulation study is performed to show the performance of the ML estimators. We discuss three real data applications related to real cancer data sets to assess the usefulness of the proposed model compared with some existing cure rate models for the sake of comparison.
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spelling doaj.art-1d3bafe7c8364804a76f4d55369fb6292023-11-24T16:27:14ZengMDPI AGMathematics2227-73902022-12-011024464310.3390/math10244643A New Cure Rate Model Based on Flory–Schulz Distribution: Application to the Cancer DataReza Azimi0Mahdy Esmailian1Diego I. Gallardo2Héctor J. Gómez3Department of Statistics And Computer Sciences, University of Mohaghegh Ardabili, Ardabil 56199-11367, IranDepartment of Statistics And Computer Sciences, University of Mohaghegh Ardabili, Ardabil 56199-11367, IranDepartamento de Matematica, Facultad de Ingenieria, Universidad de Atacama, Copiapo 1530000, ChileDepartamento de Ciencias Matemáticas y Físicas, Facultad de Ingeniería, Universidad Católica de Temuco, Temuco 4780000, ChileIn this article a new flexible survival cure rate model is introduced by assuming that the number of competing causes of the event of interest follows the Flory–Schulz distribution and the competing causes follow the generalized truncated Nadarajah–Haghighi distribution. Parameter estimation for the proposed model is derived based on the maximum likelihood estimation method. A simulation study is performed to show the performance of the ML estimators. We discuss three real data applications related to real cancer data sets to assess the usefulness of the proposed model compared with some existing cure rate models for the sake of comparison.https://www.mdpi.com/2227-7390/10/24/4643cure rate modelFlory–Schulz distributiongeneralized truncated Nadarajah–Haghighi distributioncancer datamaximum likelihood estimation
spellingShingle Reza Azimi
Mahdy Esmailian
Diego I. Gallardo
Héctor J. Gómez
A New Cure Rate Model Based on Flory–Schulz Distribution: Application to the Cancer Data
Mathematics
cure rate model
Flory–Schulz distribution
generalized truncated Nadarajah–Haghighi distribution
cancer data
maximum likelihood estimation
title A New Cure Rate Model Based on Flory–Schulz Distribution: Application to the Cancer Data
title_full A New Cure Rate Model Based on Flory–Schulz Distribution: Application to the Cancer Data
title_fullStr A New Cure Rate Model Based on Flory–Schulz Distribution: Application to the Cancer Data
title_full_unstemmed A New Cure Rate Model Based on Flory–Schulz Distribution: Application to the Cancer Data
title_short A New Cure Rate Model Based on Flory–Schulz Distribution: Application to the Cancer Data
title_sort new cure rate model based on flory schulz distribution application to the cancer data
topic cure rate model
Flory–Schulz distribution
generalized truncated Nadarajah–Haghighi distribution
cancer data
maximum likelihood estimation
url https://www.mdpi.com/2227-7390/10/24/4643
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