Bullous Lupus Erythematosus Manifesting As Erythema Multiforme
Bullous SLE has a distinctive clinical, histopathologic and immunopathologic features that together constitute a unique bullous disease phenotype. We report a 33 year old female presenting with multiple tense vesicles and bullae on normal and erythematous skin over the body and oral erosions. Palms...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2004-01-01
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| Series: | Indian Journal of Dermatology |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2004;volume=49;issue=4;spage=204;epage=206;aulast=Dhurat;type=0 |
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| author | Dhurat Rachita Kamath Vishakha R Jerajani Hemangi R Shinde Santosh S Gupta Madhuri T |
| author_facet | Dhurat Rachita Kamath Vishakha R Jerajani Hemangi R Shinde Santosh S Gupta Madhuri T |
| author_sort | Dhurat Rachita |
| collection | DOAJ |
| description | Bullous SLE has a distinctive clinical, histopathologic and immunopathologic features that together constitute a unique bullous disease phenotype. We report a 33 year old female presenting with multiple tense vesicles and bullae on normal and erythematous skin over the body and oral erosions. Palms and extremities showed typical target lesions. She had consumed NSAIDs intermittently for joint pains. She was diagnosed as bullous erythema multiforme and started on oral prednisolone but lesions failed to heal. Patient recollected a history of low grade fever and a photosensitive rash in the past. Investigations revealed positive ANA with a peripheral pattern. A skin biopsy of a vesicle showed a subepidemal blisher. Perilesional direct immunofluorescence studies showed a linear deposition of IgG, IgA and fibrin along the basement membrane zone and perivascular deposition of IgG. Lapus band test showed a linear deposition of IgG, C3, IgM and fibrin at BMZ clinching the diagnosis of bullous lupus erythematosus. |
| first_indexed | 2024-12-20T09:42:11Z |
| format | Article |
| id | doaj.art-1d3c99b1bb8149f09ed10a6fd02d381b |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-20T09:42:11Z |
| publishDate | 2004-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-1d3c99b1bb8149f09ed10a6fd02d381b2022-12-21T19:44:51ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112004-01-01494204206Bullous Lupus Erythematosus Manifesting As Erythema MultiformeDhurat RachitaKamath Vishakha RJerajani Hemangi RShinde Santosh SGupta Madhuri TBullous SLE has a distinctive clinical, histopathologic and immunopathologic features that together constitute a unique bullous disease phenotype. We report a 33 year old female presenting with multiple tense vesicles and bullae on normal and erythematous skin over the body and oral erosions. Palms and extremities showed typical target lesions. She had consumed NSAIDs intermittently for joint pains. She was diagnosed as bullous erythema multiforme and started on oral prednisolone but lesions failed to heal. Patient recollected a history of low grade fever and a photosensitive rash in the past. Investigations revealed positive ANA with a peripheral pattern. A skin biopsy of a vesicle showed a subepidemal blisher. Perilesional direct immunofluorescence studies showed a linear deposition of IgG, IgA and fibrin along the basement membrane zone and perivascular deposition of IgG. Lapus band test showed a linear deposition of IgG, C3, IgM and fibrin at BMZ clinching the diagnosis of bullous lupus erythematosus.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2004;volume=49;issue=4;spage=204;epage=206;aulast=Dhurat;type=0 |
| spellingShingle | Dhurat Rachita Kamath Vishakha R Jerajani Hemangi R Shinde Santosh S Gupta Madhuri T Bullous Lupus Erythematosus Manifesting As Erythema Multiforme Indian Journal of Dermatology |
| title | Bullous Lupus Erythematosus Manifesting As Erythema Multiforme |
| title_full | Bullous Lupus Erythematosus Manifesting As Erythema Multiforme |
| title_fullStr | Bullous Lupus Erythematosus Manifesting As Erythema Multiforme |
| title_full_unstemmed | Bullous Lupus Erythematosus Manifesting As Erythema Multiforme |
| title_short | Bullous Lupus Erythematosus Manifesting As Erythema Multiforme |
| title_sort | bullous lupus erythematosus manifesting as erythema multiforme |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2004;volume=49;issue=4;spage=204;epage=206;aulast=Dhurat;type=0 |
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