Antimicrobial Resistance: An Overview

Antibiotics are one of the greatest discoveries of medical science and have saved millions of lives since their discovery. Antimicrobial resistance is usually of acquired type and is mostly due to mutations in microbes and selection pressure from antibiotic use. Lack of adherence to drug therapi...

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Main Authors: Manoj Kumar Mitra, Anil Verma, Vijay M Katekhaye, Onkar C Swami
Format: Article
Language:English
Published: JCDR Research and Publications Pvt. Ltd. 2014-03-01
Series:National Journal of Laboratory Medicine
Subjects:
Online Access:http://www.njlm.net/articles/PDF/2003/4-%208776_F(H)_PF1(PAG)_PFA(P).pdf
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author Manoj Kumar Mitra
Anil Verma
Vijay M Katekhaye
Onkar C Swami
author_facet Manoj Kumar Mitra
Anil Verma
Vijay M Katekhaye
Onkar C Swami
author_sort Manoj Kumar Mitra
collection DOAJ
description Antibiotics are one of the greatest discoveries of medical science and have saved millions of lives since their discovery. Antimicrobial resistance is usually of acquired type and is mostly due to mutations in microbes and selection pressure from antibiotic use. Lack of adherence to drug therapies, suboptimal dosing and duration of treatment, ineffective infection control and lack of research on new antibiotics are some of the important factors responsible for development of antimicrobial resistance. Presently antimicrobial resistance is a global problem because of spread of resistant strains across the countries and continents. Economic implications of antimicrobial resistance are huge and enormous money is being spent for treatment various diseases which have become resistant to effective and cheaper older drugs. Here, we describe the epidemiology of antibiotic resistance, its major causes and consequences, and identify critical area which requires urgent action.
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spelling doaj.art-1d46b821d55642ea9666f49b5a8ccfd32022-12-22T01:06:59ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822014-03-0131111410.7860/NJLM/2014/8776:2003Antimicrobial Resistance: An OverviewManoj Kumar Mitra0Anil Verma1Vijay M Katekhaye2Onkar C Swami3Ex-Professor and Head, Department of Medicine, Former Director, Clinical Epidemiology Unit, King George Medical University, Lucknow, India.Consulting Gastroenterologist, Department of Gastroenterology Sarvodaya Hospital and Research Centre, Ghaziabad, India.Assistant Manager, Department of Medical Services, Unichem Laboratories Ltd. Unichem Bhavan, Jogeshwari (W), Mumbai, India.Head, Department of Medical Services, Unichem Laboratories Ltd. Unichem Bhavan, Jogeshwari (W), Mumbai, India.Antibiotics are one of the greatest discoveries of medical science and have saved millions of lives since their discovery. Antimicrobial resistance is usually of acquired type and is mostly due to mutations in microbes and selection pressure from antibiotic use. Lack of adherence to drug therapies, suboptimal dosing and duration of treatment, ineffective infection control and lack of research on new antibiotics are some of the important factors responsible for development of antimicrobial resistance. Presently antimicrobial resistance is a global problem because of spread of resistant strains across the countries and continents. Economic implications of antimicrobial resistance are huge and enormous money is being spent for treatment various diseases which have become resistant to effective and cheaper older drugs. Here, we describe the epidemiology of antibiotic resistance, its major causes and consequences, and identify critical area which requires urgent action.http://www.njlm.net/articles/PDF/2003/4-%208776_F(H)_PF1(PAG)_PFA(P).pdfantimicrobial resistanceantibiotic adherencerational drug useinfection
spellingShingle Manoj Kumar Mitra
Anil Verma
Vijay M Katekhaye
Onkar C Swami
Antimicrobial Resistance: An Overview
National Journal of Laboratory Medicine
antimicrobial resistance
antibiotic adherence
rational drug use
infection
title Antimicrobial Resistance: An Overview
title_full Antimicrobial Resistance: An Overview
title_fullStr Antimicrobial Resistance: An Overview
title_full_unstemmed Antimicrobial Resistance: An Overview
title_short Antimicrobial Resistance: An Overview
title_sort antimicrobial resistance an overview
topic antimicrobial resistance
antibiotic adherence
rational drug use
infection
url http://www.njlm.net/articles/PDF/2003/4-%208776_F(H)_PF1(PAG)_PFA(P).pdf
work_keys_str_mv AT manojkumarmitra antimicrobialresistanceanoverview
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AT vijaymkatekhaye antimicrobialresistanceanoverview
AT onkarcswami antimicrobialresistanceanoverview