Steroids in neuroinfection

The consequences of inflammatory response are primarily responsible for morbimortality in bacterial meningitis. Early use of steroids in these cases can reduce mortality and hearing loss and improve functional outcome without causing significant side effects. The formal recommendation towards pneumo...

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Main Author: Ronaldo Abraham
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2013-09-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001000717&lng=en&tlng=en
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author Ronaldo Abraham
author_facet Ronaldo Abraham
author_sort Ronaldo Abraham
collection DOAJ
description The consequences of inflammatory response are primarily responsible for morbimortality in bacterial meningitis. Early use of steroids in these cases can reduce mortality and hearing loss and improve functional outcome without causing significant side effects. The formal recommendation towards pneumoccocal meningitis is being extended to other forms of Bacterial Meningitis. The same thought can be applied to tuberculous meningitis. In neurocysticercosis and neuroschistosomiasis steroids are more useful than parasiticides in most cases. Despite the evidence favoring the use of steroids in herpes simplex encephalitis, it is not sufficient to definitely support such indication. Among the opportunistic infections that affect AIDS patients, neurotoxoplasmosis and progressive multifocal leukoencephalopaty are those most often considered for the use of steroids; steroids are safe to use, but no definite benefit could be demonstrated in both conditions.
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spelling doaj.art-1d4b91e23af64ef5b7694eeb15a4e50f2022-12-22T03:12:25ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272013-09-01719B71772110.1590/0004-282X20130158S0004-282X2013001000717Steroids in neuroinfectionRonaldo AbrahamThe consequences of inflammatory response are primarily responsible for morbimortality in bacterial meningitis. Early use of steroids in these cases can reduce mortality and hearing loss and improve functional outcome without causing significant side effects. The formal recommendation towards pneumoccocal meningitis is being extended to other forms of Bacterial Meningitis. The same thought can be applied to tuberculous meningitis. In neurocysticercosis and neuroschistosomiasis steroids are more useful than parasiticides in most cases. Despite the evidence favoring the use of steroids in herpes simplex encephalitis, it is not sufficient to definitely support such indication. Among the opportunistic infections that affect AIDS patients, neurotoxoplasmosis and progressive multifocal leukoencephalopaty are those most often considered for the use of steroids; steroids are safe to use, but no definite benefit could be demonstrated in both conditions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001000717&lng=en&tlng=ensteroidsbacterial meningitistuberculosisneuroparasitosisAIDSesteroidesmeningite bacterianatuberculoseneuroparasitosesAIDS
spellingShingle Ronaldo Abraham
Steroids in neuroinfection
Arquivos de Neuro-Psiquiatria
steroids
bacterial meningitis
tuberculosis
neuroparasitosis
AIDS
esteroides
meningite bacteriana
tuberculose
neuroparasitoses
AIDS
title Steroids in neuroinfection
title_full Steroids in neuroinfection
title_fullStr Steroids in neuroinfection
title_full_unstemmed Steroids in neuroinfection
title_short Steroids in neuroinfection
title_sort steroids in neuroinfection
topic steroids
bacterial meningitis
tuberculosis
neuroparasitosis
AIDS
esteroides
meningite bacteriana
tuberculose
neuroparasitoses
AIDS
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001000717&lng=en&tlng=en
work_keys_str_mv AT ronaldoabraham steroidsinneuroinfection