Steroids in neuroinfection
The consequences of inflammatory response are primarily responsible for morbimortality in bacterial meningitis. Early use of steroids in these cases can reduce mortality and hearing loss and improve functional outcome without causing significant side effects. The formal recommendation towards pneumo...
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Format: | Article |
Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
2013-09-01
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Series: | Arquivos de Neuro-Psiquiatria |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001000717&lng=en&tlng=en |
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author | Ronaldo Abraham |
author_facet | Ronaldo Abraham |
author_sort | Ronaldo Abraham |
collection | DOAJ |
description | The consequences of inflammatory response are primarily responsible for morbimortality in bacterial meningitis. Early use of steroids in these cases can reduce mortality and hearing loss and improve functional outcome without causing significant side effects. The formal recommendation towards pneumoccocal meningitis is being extended to other forms of Bacterial Meningitis. The same thought can be applied to tuberculous meningitis. In neurocysticercosis and neuroschistosomiasis steroids are more useful than parasiticides in most cases. Despite the evidence favoring the use of steroids in herpes simplex encephalitis, it is not sufficient to definitely support such indication. Among the opportunistic infections that affect AIDS patients, neurotoxoplasmosis and progressive multifocal leukoencephalopaty are those most often considered for the use of steroids; steroids are safe to use, but no definite benefit could be demonstrated in both conditions. |
first_indexed | 2024-04-12T23:25:44Z |
format | Article |
id | doaj.art-1d4b91e23af64ef5b7694eeb15a4e50f |
institution | Directory Open Access Journal |
issn | 1678-4227 |
language | English |
last_indexed | 2024-04-12T23:25:44Z |
publishDate | 2013-09-01 |
publisher | Academia Brasileira de Neurologia (ABNEURO) |
record_format | Article |
series | Arquivos de Neuro-Psiquiatria |
spelling | doaj.art-1d4b91e23af64ef5b7694eeb15a4e50f2022-12-22T03:12:25ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272013-09-01719B71772110.1590/0004-282X20130158S0004-282X2013001000717Steroids in neuroinfectionRonaldo AbrahamThe consequences of inflammatory response are primarily responsible for morbimortality in bacterial meningitis. Early use of steroids in these cases can reduce mortality and hearing loss and improve functional outcome without causing significant side effects. The formal recommendation towards pneumoccocal meningitis is being extended to other forms of Bacterial Meningitis. The same thought can be applied to tuberculous meningitis. In neurocysticercosis and neuroschistosomiasis steroids are more useful than parasiticides in most cases. Despite the evidence favoring the use of steroids in herpes simplex encephalitis, it is not sufficient to definitely support such indication. Among the opportunistic infections that affect AIDS patients, neurotoxoplasmosis and progressive multifocal leukoencephalopaty are those most often considered for the use of steroids; steroids are safe to use, but no definite benefit could be demonstrated in both conditions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001000717&lng=en&tlng=ensteroidsbacterial meningitistuberculosisneuroparasitosisAIDSesteroidesmeningite bacterianatuberculoseneuroparasitosesAIDS |
spellingShingle | Ronaldo Abraham Steroids in neuroinfection Arquivos de Neuro-Psiquiatria steroids bacterial meningitis tuberculosis neuroparasitosis AIDS esteroides meningite bacteriana tuberculose neuroparasitoses AIDS |
title | Steroids in neuroinfection |
title_full | Steroids in neuroinfection |
title_fullStr | Steroids in neuroinfection |
title_full_unstemmed | Steroids in neuroinfection |
title_short | Steroids in neuroinfection |
title_sort | steroids in neuroinfection |
topic | steroids bacterial meningitis tuberculosis neuroparasitosis AIDS esteroides meningite bacteriana tuberculose neuroparasitoses AIDS |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001000717&lng=en&tlng=en |
work_keys_str_mv | AT ronaldoabraham steroidsinneuroinfection |