A Rare Case Report of Clear Cell Variant of Oral Squamous Cell Carcinoma
Clear cell squamous cell carcinoma (SCC) is an extremely rare heterogenous group of malignant tumour with incompletely understood aetiology. We, hereby present a case of clear cell variant of squamous carcinoma on buccal mucosa in 52-year-old male patient. Histopathology showed sheets of squamous...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2014-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/5339/11536_CE(RA1)_F(T)_PF1(NJAK)_PFA(P)_OLF_PF2(PAG).pdf |
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| author | Purshotam Nainani Harkanwal Preet Singh Aparna Paliwal Neelu Nagpal |
| author_facet | Purshotam Nainani Harkanwal Preet Singh Aparna Paliwal Neelu Nagpal |
| author_sort | Purshotam Nainani |
| collection | DOAJ |
| description | Clear cell squamous cell carcinoma (SCC) is an extremely rare heterogenous group of malignant tumour with incompletely understood
aetiology. We, hereby present a case of clear cell variant of squamous carcinoma on buccal mucosa in 52-year-old male patient.
Histopathology showed sheets of squamous cells with clear cell differentiation and malignant features. Histochemical findings showed
negative staining for Periodic Acid-Schiff (PAS), mucicarmine and Oil Red O. Immunohistochemical investigations revealed positive staining
for CK 8-18 and negative for S-100. We conclude by emphasizing on the need of careful analysis of all the histopathological and IHC
investigations. To predict the exact prognosis of this rare variant more number of case reports are expected to be published in future. |
| first_indexed | 2024-12-11T12:44:13Z |
| format | Article |
| id | doaj.art-1d4baa53348848319b03a3437b68a0ee |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T12:44:13Z |
| publishDate | 2014-12-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-1d4baa53348848319b03a3437b68a0ee2022-12-22T01:06:52ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-12-01812QD07QD0910.7860/JCDR/2014/11536.5339A Rare Case Report of Clear Cell Variant of Oral Squamous Cell CarcinomaPurshotam Nainani0Harkanwal Preet Singh1Aparna Paliwal2Neelu Nagpal3Professor and Head, Department of Oral Pathology, RKDF Dental College, Bhopal, M.P, India.Senior Lecturer, Department of Oral Pathology, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India.Reader, Department of Oral Pathology, RKDF Dental College, Bhopal, M.P, India.Senior Lecturer, Department of Oral Pathology, RKDF Dental College, Bhopal, M.P, India.Clear cell squamous cell carcinoma (SCC) is an extremely rare heterogenous group of malignant tumour with incompletely understood aetiology. We, hereby present a case of clear cell variant of squamous carcinoma on buccal mucosa in 52-year-old male patient. Histopathology showed sheets of squamous cells with clear cell differentiation and malignant features. Histochemical findings showed negative staining for Periodic Acid-Schiff (PAS), mucicarmine and Oil Red O. Immunohistochemical investigations revealed positive staining for CK 8-18 and negative for S-100. We conclude by emphasizing on the need of careful analysis of all the histopathological and IHC investigations. To predict the exact prognosis of this rare variant more number of case reports are expected to be published in future.https://jcdr.net/articles/PDF/5339/11536_CE(RA1)_F(T)_PF1(NJAK)_PFA(P)_OLF_PF2(PAG).pdfclear cell carcinomadermatopathologyhydropic degenerationskinulcers |
| spellingShingle | Purshotam Nainani Harkanwal Preet Singh Aparna Paliwal Neelu Nagpal A Rare Case Report of Clear Cell Variant of Oral Squamous Cell Carcinoma Journal of Clinical and Diagnostic Research clear cell carcinoma dermatopathology hydropic degeneration skin ulcers |
| title | A Rare Case Report of Clear Cell Variant of Oral Squamous Cell Carcinoma |
| title_full | A Rare Case Report of Clear Cell Variant of Oral Squamous Cell Carcinoma |
| title_fullStr | A Rare Case Report of Clear Cell Variant of Oral Squamous Cell Carcinoma |
| title_full_unstemmed | A Rare Case Report of Clear Cell Variant of Oral Squamous Cell Carcinoma |
| title_short | A Rare Case Report of Clear Cell Variant of Oral Squamous Cell Carcinoma |
| title_sort | rare case report of clear cell variant of oral squamous cell carcinoma |
| topic | clear cell carcinoma dermatopathology hydropic degeneration skin ulcers |
| url | https://jcdr.net/articles/PDF/5339/11536_CE(RA1)_F(T)_PF1(NJAK)_PFA(P)_OLF_PF2(PAG).pdf |
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