A BRCA2 germline mutation and high expression of immune checkpoints in a TNBC patient

A BRCA2 germline mutation and high expression of immune checkpoints in a TNBC patient

Abstract Triple-negative breast cancer (TNBC) is the most aggressive subtype of mammary carcinoma. Here, we describe a case of an 81-year-old female diagnosed with ductal triple negative breast cancer with a germline pathogenic variant in BReast CAncer gene2 (BRCA2). Genetic testing also revealed th...

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Bibliographic Details
Main Authors: Yuyi Han, Valentina Rovella, Artem Smirnov, Oreste Claudio Buonomo, Alessandro Mauriello, Tommaso Perretta, Yufang Shi, Jonathan Woodmsith, Julia Bischof, TOR CENTRE, Gerry Melino, Eleonora Candi, Francesca Bernassola
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01651-3

Internet

https://doi.org/10.1038/s41420-023-01651-3

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