Comparative Effects of Deferiprone and Salinomycin on Lead-Induced Disturbance in the Homeostasis of Intrarenal Essential Elements in Mice

Comparative Effects of Deferiprone and Salinomycin on Lead-Induced Disturbance in the Homeostasis of Intrarenal Essential Elements in Mice

Lead (Pb) exposure induces severe nephrotoxic effects in humans and animals. Herein, we compare the effects of two chelating agents, salinomycin and deferiprone, on Pb-induced renal alterations in mice and in the homeostasis of essential elements. Adult male mice (<i>Institute of Cancer Resear...

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Bibliographic Details
Main Authors: Yordanka Gluhcheva, Irena Pashkunova-Martic, Martin Schaier, Ivelin Vladov, Silviya Stoykova, Emilia Petrova, Ekaterina Pavlova, Peter Dorkov, Thomas H. Helbich, Bernhard Keppler, Juliana Ivanova
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
deferiprone
salinomycin
lead
essential elements
kidneys
Online Access:https://www.mdpi.com/1422-0067/23/8/4368

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