New Metabolites of Coumarin Detected in Human Urine Using Ultra Performance Liquid Chromatography/Quadrupole-Time-of-Flight Tandem Mass Spectrometry

New Metabolites of Coumarin Detected in Human Urine Using Ultra Performance Liquid Chromatography/Quadrupole-Time-of-Flight Tandem Mass Spectrometry

Coumarin (1,2-benzopyrone) is a natural compound whose metabolism in humans was established in the 1970s. However, a new metabolite was recently identified in human plasma, indicating that the metabolism of coumarin has not been completely elucidated. To complement the knowledge of its metabolism, a...

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Bibliographic Details
Main Authors: Letícia Paula Leonart, João Cleverson Gasparetto, Flávia Lada Degaut Pontes, Letícia Bonancio Cerqueira, Thais Martins Guimarães de Francisco, Roberto Pontarolo
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Molecules
Subjects:
coumarin
metabolism
urine
humans
chromatography
high pressure liquid
mass spectrometry
Online Access:https://www.mdpi.com/1420-3049/22/11/2031

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