Epidemiology and Survival of Kaposi’s Sarcoma by Race in the United States: A Surveillance, Epidemiology, and End Results Database Analysis
Sara D Ragi,1 Isabelle Moseley,1 Samantha Ouellette,2 Babar Rao2 1The Warren Alpert Medical School of Brown University, Providence, RI, USA; 2Department of Dermatology, Robert Wood Johnson Medical School, New Brunswick, NJ, USACorrespondence: Sara D Ragi, Email sara_ragi@brown.eduAbstract: The intro...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-08-01
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| Series: | Clinical, Cosmetic and Investigational Dermatology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/epidemiology-and-survival-of-kaposis-sarcoma-by-race-in-the-united-sta-peer-reviewed-fulltext-article-CCID |
| _version_ | 1811340062574510080 |
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| author | Ragi SD Moseley I Ouellette S Rao B |
| author_facet | Ragi SD Moseley I Ouellette S Rao B |
| author_sort | Ragi SD |
| collection | DOAJ |
| description | Sara D Ragi,1 Isabelle Moseley,1 Samantha Ouellette,2 Babar Rao2 1The Warren Alpert Medical School of Brown University, Providence, RI, USA; 2Department of Dermatology, Robert Wood Johnson Medical School, New Brunswick, NJ, USACorrespondence: Sara D Ragi, Email sara_ragi@brown.eduAbstract: The introduction of highly active antiretroviral treatment (HAART) for acquired immunodeficiency syndrome (AIDS) has led to a significant decrease in the incidence of Kaposi’s sarcoma (KS) in recent years. However, a concomitant increase in racial disparities in KS has arisen. Here, we analyze data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program for epidemiology and survival of Kaposi’s sarcoma by race. The highest incidence was observed among Black patients (incidence rate (IR), 1.189; 95% confidence interval (CI), 1.092– 1.189), followed by White patients (IR, 0.486; 95% CI, 0.473– 0.498). Relative survival at 1, 3, and 5 years differed significantly by race, with White patients having the highest survival rates (84.26%, 77.79%, and 74.79% at 1, 3, and 5 years respectively) and Black patients demonstrating the lowest (71.50%, 61.37%, and 57.38%), with intermediate survival rates in Asians/Pacific Islanders (AAPI) (80.62%, 71.19%, and 67.28%) and American Indians/Alaska Natives (AIAN) (80.56%, 61.45%, and 61.45%). We conclude that there are significant racial disparities in the incidence, epidemiology, and survival of KS.Keywords: Kaposi’s sarcoma, racial disparities, race, cancer, soft tissue sarcoma, surveillance, epidemiology, end results program, epidemiology |
| first_indexed | 2024-04-13T18:35:56Z |
| format | Article |
| id | doaj.art-1d4faf3ffb654fa6bf96237f51e66068 |
| institution | Directory Open Access Journal |
| issn | 1178-7015 |
| language | English |
| last_indexed | 2024-04-13T18:35:56Z |
| publishDate | 2022-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical, Cosmetic and Investigational Dermatology |
| spelling | doaj.art-1d4faf3ffb654fa6bf96237f51e660682022-12-22T02:34:52ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152022-08-01Volume 151681168577497Epidemiology and Survival of Kaposi’s Sarcoma by Race in the United States: A Surveillance, Epidemiology, and End Results Database AnalysisRagi SDMoseley IOuellette SRao BSara D Ragi,1 Isabelle Moseley,1 Samantha Ouellette,2 Babar Rao2 1The Warren Alpert Medical School of Brown University, Providence, RI, USA; 2Department of Dermatology, Robert Wood Johnson Medical School, New Brunswick, NJ, USACorrespondence: Sara D Ragi, Email sara_ragi@brown.eduAbstract: The introduction of highly active antiretroviral treatment (HAART) for acquired immunodeficiency syndrome (AIDS) has led to a significant decrease in the incidence of Kaposi’s sarcoma (KS) in recent years. However, a concomitant increase in racial disparities in KS has arisen. Here, we analyze data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program for epidemiology and survival of Kaposi’s sarcoma by race. The highest incidence was observed among Black patients (incidence rate (IR), 1.189; 95% confidence interval (CI), 1.092– 1.189), followed by White patients (IR, 0.486; 95% CI, 0.473– 0.498). Relative survival at 1, 3, and 5 years differed significantly by race, with White patients having the highest survival rates (84.26%, 77.79%, and 74.79% at 1, 3, and 5 years respectively) and Black patients demonstrating the lowest (71.50%, 61.37%, and 57.38%), with intermediate survival rates in Asians/Pacific Islanders (AAPI) (80.62%, 71.19%, and 67.28%) and American Indians/Alaska Natives (AIAN) (80.56%, 61.45%, and 61.45%). We conclude that there are significant racial disparities in the incidence, epidemiology, and survival of KS.Keywords: Kaposi’s sarcoma, racial disparities, race, cancer, soft tissue sarcoma, surveillance, epidemiology, end results program, epidemiologyhttps://www.dovepress.com/epidemiology-and-survival-of-kaposis-sarcoma-by-race-in-the-united-sta-peer-reviewed-fulltext-article-CCIDkaposi’s sarcomaracial disparitiesracecancersoft tissue sarcomasurveillanceepidemiologyand end results programepidemiology |
| spellingShingle | Ragi SD Moseley I Ouellette S Rao B Epidemiology and Survival of Kaposi’s Sarcoma by Race in the United States: A Surveillance, Epidemiology, and End Results Database Analysis Clinical, Cosmetic and Investigational Dermatology kaposi’s sarcoma racial disparities race cancer soft tissue sarcoma surveillance epidemiology and end results program epidemiology |
| title | Epidemiology and Survival of Kaposi’s Sarcoma by Race in the United States: A Surveillance, Epidemiology, and End Results Database Analysis |
| title_full | Epidemiology and Survival of Kaposi’s Sarcoma by Race in the United States: A Surveillance, Epidemiology, and End Results Database Analysis |
| title_fullStr | Epidemiology and Survival of Kaposi’s Sarcoma by Race in the United States: A Surveillance, Epidemiology, and End Results Database Analysis |
| title_full_unstemmed | Epidemiology and Survival of Kaposi’s Sarcoma by Race in the United States: A Surveillance, Epidemiology, and End Results Database Analysis |
| title_short | Epidemiology and Survival of Kaposi’s Sarcoma by Race in the United States: A Surveillance, Epidemiology, and End Results Database Analysis |
| title_sort | epidemiology and survival of kaposi rsquo s sarcoma by race in the united states a surveillance epidemiology and end results database analysis |
| topic | kaposi’s sarcoma racial disparities race cancer soft tissue sarcoma surveillance epidemiology and end results program epidemiology |
| url | https://www.dovepress.com/epidemiology-and-survival-of-kaposis-sarcoma-by-race-in-the-united-sta-peer-reviewed-fulltext-article-CCID |
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