Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case report

Purpose: To report on a case of diffuse unilateral subacute neuroretinitis (DUSN) that was successfully treated with a short course of oral albendazole. Observations: A 51-year-old male presented with severe visual loss secondary to DUSN associated with a positive Toxocara serology. Because the para...

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Main Authors: Claudia Amaral, Hiram Jimenez, Pedro Davila, Jan P. Ulloa-Padilla, Humberto M. Guiot, Armando L. Oliver
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993621000451
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author Claudia Amaral
Hiram Jimenez
Pedro Davila
Jan P. Ulloa-Padilla
Humberto M. Guiot
Armando L. Oliver
author_facet Claudia Amaral
Hiram Jimenez
Pedro Davila
Jan P. Ulloa-Padilla
Humberto M. Guiot
Armando L. Oliver
author_sort Claudia Amaral
collection DOAJ
description Purpose: To report on a case of diffuse unilateral subacute neuroretinitis (DUSN) that was successfully treated with a short course of oral albendazole. Observations: A 51-year-old male presented with severe visual loss secondary to DUSN associated with a positive Toxocara serology. Because the parasite could not be detected on fundoscopy, first-line treatment with photocoagulation could not be administered. Treatment with a 6-day course of oral albendazole resulted in the resolution of DUSN as well as the restoration of visual acuity. Conclusion and importance: Although DUSN is characterized by the presence of a parasitic organism in the retina, there are cases in which the parasite is not visible. Albendazole has been used to treat such cases, but a standard treatment regimen has not been determined yet. Our case suggests that the resolution of DUSN can be achieved with short-term albendazole therapy.
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spelling doaj.art-1d55829365c8444a8e89c0053adfc6e22022-12-21T22:53:07ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362021-06-0122101054Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case reportClaudia Amaral0Hiram Jimenez1Pedro Davila2Jan P. Ulloa-Padilla3Humberto M. Guiot4Armando L. Oliver5University of Puerto Rico, Medical Sciences Campus, School of Medicine, San Juan, PR, USAUniversity of Puerto Rico, Medical Sciences Campus, School of Medicine, San Juan, PR, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, San Juan, PR, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, San Juan, PR, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Medicine, Infectious Diseases Division, San Juan, PR, USA; University of Puerto Rico, Medical Sciences Campus, Department of Microbiology and Medical Zoology, San Juan, PR, USAUniversity of Puerto Rico, Medical Sciences Campus, Department of Ophthalmology, San Juan, PR, USA; Corresponding author. UPR Department of Ophthalmology, PO BOX 3650689, San Juan, PR, 00936, USA.Purpose: To report on a case of diffuse unilateral subacute neuroretinitis (DUSN) that was successfully treated with a short course of oral albendazole. Observations: A 51-year-old male presented with severe visual loss secondary to DUSN associated with a positive Toxocara serology. Because the parasite could not be detected on fundoscopy, first-line treatment with photocoagulation could not be administered. Treatment with a 6-day course of oral albendazole resulted in the resolution of DUSN as well as the restoration of visual acuity. Conclusion and importance: Although DUSN is characterized by the presence of a parasitic organism in the retina, there are cases in which the parasite is not visible. Albendazole has been used to treat such cases, but a standard treatment regimen has not been determined yet. Our case suggests that the resolution of DUSN can be achieved with short-term albendazole therapy.http://www.sciencedirect.com/science/article/pii/S2451993621000451Diffuse unilateral subacute neuroretinitisDUSNToxocaraAlbendazole
spellingShingle Claudia Amaral
Hiram Jimenez
Pedro Davila
Jan P. Ulloa-Padilla
Humberto M. Guiot
Armando L. Oliver
Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case report
American Journal of Ophthalmology Case Reports
Diffuse unilateral subacute neuroretinitis
DUSN
Toxocara
Albendazole
title Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case report
title_full Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case report
title_fullStr Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case report
title_full_unstemmed Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case report
title_short Short-term oral albendazole therapy for diffuse unilateral subacute neuroretinitis: A case report
title_sort short term oral albendazole therapy for diffuse unilateral subacute neuroretinitis a case report
topic Diffuse unilateral subacute neuroretinitis
DUSN
Toxocara
Albendazole
url http://www.sciencedirect.com/science/article/pii/S2451993621000451
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