The dimeric Golgi protein Gorab binds to Sas6 as a monomer to mediate centriole duplication
The duplication and ninefold symmetry of the Drosophila centriole requires that the cartwheel molecule, Sas6, physically associates with Gorab, a trans-Golgi component. How Gorab achieves these disparate associations is unclear. Here, we use hydrogen–deuterium exchange mass spectrometry to define Go...
Main Authors: | Agnieszka Fatalska, Emma Stepinac, Magdalena Richter, Levente Kovacs, Zbigniew Pietras, Martin Puchinger, Gang Dong, Michal Dadlez, David M Glover |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/57241 |
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