Dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel disease

Dendritic cells play crucial roles in the control of inflammation and immune tolerance in the gut. We aimed to investigate the effects of tumor necrosis factor alpha (TNFa) inhibitors on intestinal dendritic cells in patients with inflammatory bowel disease and the potential role of intestinal dendr...

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Main Authors: Smrekar Natasa, Drobne David, Smid Lojze M., Ferkolj Ivan, Stabuc Borut, Ihan Alojz, Kopitar Andreja Natasa
Format: Article
Language:English
Published: Sciendo 2018-11-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2018-0045
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author Smrekar Natasa
Drobne David
Smid Lojze M.
Ferkolj Ivan
Stabuc Borut
Ihan Alojz
Kopitar Andreja Natasa
author_facet Smrekar Natasa
Drobne David
Smid Lojze M.
Ferkolj Ivan
Stabuc Borut
Ihan Alojz
Kopitar Andreja Natasa
author_sort Smrekar Natasa
collection DOAJ
description Dendritic cells play crucial roles in the control of inflammation and immune tolerance in the gut. We aimed to investigate the effects of tumor necrosis factor alpha (TNFa) inhibitors on intestinal dendritic cells in patients with inflammatory bowel disease and the potential role of intestinal dendritic cells in predicting the response to treatment.
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spelling doaj.art-1d59c119fe3e48118ae560c2788138c22022-12-21T22:40:30ZengSciendoRadiology and Oncology1581-32072018-11-0152444345210.2478/raon-2018-0045raon-2018-0045Dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel diseaseSmrekar Natasa0Drobne David1Smid Lojze M.2Ferkolj Ivan3Stabuc Borut4Ihan Alojz5Kopitar Andreja Natasa6Department of Gastroenterology and Hepatology, University Medical Centre, Ljubljana, SloveniaDepartment of Gastroenterology and Hepatology, University Medical Centre, Ljubljana, SloveniaDepartment of Gastroenterology and Hepatology, University Medical Centre, Ljubljana, SloveniaDepartment of Gastroenterology and Hepatology, University Medical Centre, Ljubljana, SloveniaDepartment of Gastroenterology and Hepatology, University Medical Centre, Ljubljana, SloveniaInstitutes of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, SloveniaInstitutes of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, SloveniaDendritic cells play crucial roles in the control of inflammation and immune tolerance in the gut. We aimed to investigate the effects of tumor necrosis factor alpha (TNFa) inhibitors on intestinal dendritic cells in patients with inflammatory bowel disease and the potential role of intestinal dendritic cells in predicting the response to treatment.https://doi.org/10.2478/raon-2018-0045inflammatory bowel diseasedendritic cellstumor necrosis factor-alpha inhibitorscolon cancer
spellingShingle Smrekar Natasa
Drobne David
Smid Lojze M.
Ferkolj Ivan
Stabuc Borut
Ihan Alojz
Kopitar Andreja Natasa
Dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel disease
Radiology and Oncology
inflammatory bowel disease
dendritic cells
tumor necrosis factor-alpha inhibitors
colon cancer
title Dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel disease
title_full Dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel disease
title_fullStr Dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel disease
title_full_unstemmed Dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel disease
title_short Dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel disease
title_sort dendritic cell profiles in the inflamed colonic mucosa predict the responses to tumor necrosis factor alpha inhibitors in inflammatory bowel disease
topic inflammatory bowel disease
dendritic cells
tumor necrosis factor-alpha inhibitors
colon cancer
url https://doi.org/10.2478/raon-2018-0045
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