Animal models of prenatal immune challenge and their contribution to the study of schizophrenia: a systematic review

Animal models of prenatal immune challenge and their contribution to the study of schizophrenia: a systematic review

Prenatal immune challenge (PIC) in pregnant rodents produces offspring with abnormalities in behavior, histology, and gene expression that are reminiscent of schizophrenia and autism. Based on this, the goal of this article was to review the main contributions of PIC models, especially the one using...

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Bibliographic Details
Main Authors: D.S. Macêdo, D.P. Araújo, L.R.L. Sampaio, S.M.M. Vasconcelos, P.M.G. Sales, F.C.F. Sousa, J.E. Hallak, J.A. Crippa, A.F. Carvalho
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Schizophrenia
Animal models
Neurodevelopment
Prenatal immune activation
Poly-I:C
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000300001&lng=en&tlng=en

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