A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpi

A new sesquiterpene lactone (1) and a new aromatic glycoside (2), together with three known compounds (3–5) were isolated from the stem bark of Illicium difengpi K. I. B et K. I. M. Their structures were determined by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and chemical methods. The...

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Bibliographic Details
Main Authors: Lei Fang, Xiao-jing Wang, Shuang-gang Ma, Shi-shan Yu
Format: Article
Language:English
Published: Elsevier 2011-10-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383511000657
Description
Summary:A new sesquiterpene lactone (1) and a new aromatic glycoside (2), together with three known compounds (3–5) were isolated from the stem bark of Illicium difengpi K. I. B et K. I. M. Their structures were determined by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and chemical methods. The absolute configuration of the secondary alcohol in 1 was confirmed by Mosher's method. Compound 2 exhibited significant anti-inflammatory activity with IC50 value of 6.72 μmol/L.
ISSN:2211-3835
2211-3843