A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpi
A new sesquiterpene lactone (1) and a new aromatic glycoside (2), together with three known compounds (3–5) were isolated from the stem bark of Illicium difengpi K. I. B et K. I. M. Their structures were determined by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and chemical methods. The...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2011-10-01
|
| Series: | Acta Pharmaceutica Sinica B |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383511000657 |
| _version_ | 1811216669377298432 |
|---|---|
| author | Lei Fang Xiao-jing Wang Shuang-gang Ma Shi-shan Yu |
| author_facet | Lei Fang Xiao-jing Wang Shuang-gang Ma Shi-shan Yu |
| author_sort | Lei Fang |
| collection | DOAJ |
| description | A new sesquiterpene lactone (1) and a new aromatic glycoside (2), together with three known compounds (3–5) were isolated from the stem bark of Illicium difengpi K. I. B et K. I. M. Their structures were determined by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and chemical methods. The absolute configuration of the secondary alcohol in 1 was confirmed by Mosher's method. Compound 2 exhibited significant anti-inflammatory activity with IC50 value of 6.72 μmol/L. |
| first_indexed | 2024-04-12T06:42:15Z |
| format | Article |
| id | doaj.art-1d5ca4f86d234cb0bb168aebbada3429 |
| institution | Directory Open Access Journal |
| issn | 2211-3835 2211-3843 |
| language | English |
| last_indexed | 2024-04-12T06:42:15Z |
| publishDate | 2011-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Acta Pharmaceutica Sinica B |
| spelling | doaj.art-1d5ca4f86d234cb0bb168aebbada34292022-12-22T03:43:40ZengElsevierActa Pharmaceutica Sinica B2211-38352211-38432011-10-011317818310.1016/j.apsb.2011.08.002A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpiLei Fang0Xiao-jing Wang1Shuang-gang Ma2Shi-shan Yu3State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, ChinaState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, ChinaState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, ChinaState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, ChinaA new sesquiterpene lactone (1) and a new aromatic glycoside (2), together with three known compounds (3–5) were isolated from the stem bark of Illicium difengpi K. I. B et K. I. M. Their structures were determined by spectroscopic methods, including 1D and 2D NMR, HRESIMS, and chemical methods. The absolute configuration of the secondary alcohol in 1 was confirmed by Mosher's method. Compound 2 exhibited significant anti-inflammatory activity with IC50 value of 6.72 μmol/L.http://www.sciencedirect.com/science/article/pii/S2211383511000657Illicium difengpiSesquiterpene lactoneAromatic glycosideMosher's methodAnti-inflammatory activities |
| spellingShingle | Lei Fang Xiao-jing Wang Shuang-gang Ma Shi-shan Yu A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpi Acta Pharmaceutica Sinica B Illicium difengpi Sesquiterpene lactone Aromatic glycoside Mosher's method Anti-inflammatory activities |
| title | A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpi |
| title_full | A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpi |
| title_fullStr | A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpi |
| title_full_unstemmed | A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpi |
| title_short | A new sesquiterpene lactone and a new aromatic glycoside from Illicium difengpi |
| title_sort | new sesquiterpene lactone and a new aromatic glycoside from illicium difengpi |
| topic | Illicium difengpi Sesquiterpene lactone Aromatic glycoside Mosher's method Anti-inflammatory activities |
| url | http://www.sciencedirect.com/science/article/pii/S2211383511000657 |
| work_keys_str_mv | AT leifang anewsesquiterpenelactoneandanewaromaticglycosidefromilliciumdifengpi AT xiaojingwang anewsesquiterpenelactoneandanewaromaticglycosidefromilliciumdifengpi AT shuanggangma anewsesquiterpenelactoneandanewaromaticglycosidefromilliciumdifengpi AT shishanyu anewsesquiterpenelactoneandanewaromaticglycosidefromilliciumdifengpi AT leifang newsesquiterpenelactoneandanewaromaticglycosidefromilliciumdifengpi AT xiaojingwang newsesquiterpenelactoneandanewaromaticglycosidefromilliciumdifengpi AT shuanggangma newsesquiterpenelactoneandanewaromaticglycosidefromilliciumdifengpi AT shishanyu newsesquiterpenelactoneandanewaromaticglycosidefromilliciumdifengpi |