Chemokines: a new dendritic cell signal for T cell activation

Dendritic cells (DCs) are the main inducers and regulators of cytotoxic T lymphocyte (CTL) responses against viruses and tumors. One checkpoint to avoid misguided CTL activation, which might damage healthy cells of the body, is the necessity for multiple activation signals, involving both antigenic...

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Bibliographic Details
Main Authors: Christoph A Thaiss, Verena eSemmling, Lars eFranken, Hermann eWagner, Christian eKurts
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00031/full