PGAM5 deacetylation mediated by SIRT2 facilitates lipid metabolism and liver cancer proliferation

PGAM5 deacetylation mediated by SIRT2 facilitates lipid metabolism and liver cancer proliferation

Tumor metabolic reprogramming and epigenetic modification work together to promote tumorigenesis and development. Protein lysine acetylation, which affects a variety of biological functions of proteins, plays an important role under physiol...

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Bibliographic Details
Main Authors: Fu Gongyu, Li Shi-Ting, Jiang Zetan, Mao Qiankun, Xiong Nanchi, Li Xiang, Hao Yijie, Zhang Huafeng
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-08-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
metabolic reprograming
PGAM5
protein acetylation
SIRT2
ME1
liver cancer
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023155

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