Evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of Nigerian indigenous dogs
Osteogenic potential of autologous bone marrow aspirates was evaluated on transverse tibia fractures of 12 Nigeria indigenous dogs presented to University of Nigeria Veterinary Teaching Hospital, Nsukka (UNVTH). They were assigned into four groups: single application group (Group1; n = 3), double ap...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2018-01-01
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| Series: | Journal of Applied Animal Research |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09712119.2017.1408466 |
| _version_ | 1811195518250909696 |
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| author | Theophilus Okafor Nnaji Innocent Nwaogu Nnenna Ugwu Chioma Onyenekwe |
| author_facet | Theophilus Okafor Nnaji Innocent Nwaogu Nnenna Ugwu Chioma Onyenekwe |
| author_sort | Theophilus Okafor Nnaji |
| collection | DOAJ |
| description | Osteogenic potential of autologous bone marrow aspirates was evaluated on transverse tibia fractures of 12 Nigeria indigenous dogs presented to University of Nigeria Veterinary Teaching Hospital, Nsukka (UNVTH). They were assigned into four groups: single application group (Group1; n = 3), double application group (Group 2; n = 3), triple application group (Group 2; n = 3) and the control group (Group 3; n = 3). The fractures were immobilized with Steinmann intramedullary pins in a normograde manner. The patients were then treated as follows: Group 1: with autologous bone marrow aspirate on the day of surgery; Group 2: with autologous bone marrow aspirate on days 0 and 14 post surgery; Group 3: with autologous bone marrow aspirate on days 0, 14 and 28 post surgery; Group 4: 1 ml normal saline was applied on the fracture site. Post-treatment radiographs of the fractures were taken on weeks 1, 2, 4, 7 and 10. The rate of healing was compared using radiographic union scale for tibia scores. The results showed a significant difference (p < .05) in the healing of the treated groups and the control at week 7 post surgery. There was however no significant (p > .05) difference in the healing of the fractures with single and the multiple applications. |
| first_indexed | 2024-04-12T00:44:38Z |
| format | Article |
| id | doaj.art-1d605b04bda0487597981ed1d45b9db3 |
| institution | Directory Open Access Journal |
| issn | 0971-2119 0974-1844 |
| language | English |
| last_indexed | 2024-04-12T00:44:38Z |
| publishDate | 2018-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Applied Animal Research |
| spelling | doaj.art-1d605b04bda0487597981ed1d45b9db32022-12-22T03:54:55ZengTaylor & Francis GroupJournal of Applied Animal Research0971-21190974-18442018-01-0146182883410.1080/09712119.2017.14084661408466Evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of Nigerian indigenous dogsTheophilus Okafor Nnaji0Innocent Nwaogu1Nnenna Ugwu2Chioma Onyenekwe3University of NigeriaUniversity of NigeriaUniversity of NigeriaUniversity of NigeriaOsteogenic potential of autologous bone marrow aspirates was evaluated on transverse tibia fractures of 12 Nigeria indigenous dogs presented to University of Nigeria Veterinary Teaching Hospital, Nsukka (UNVTH). They were assigned into four groups: single application group (Group1; n = 3), double application group (Group 2; n = 3), triple application group (Group 2; n = 3) and the control group (Group 3; n = 3). The fractures were immobilized with Steinmann intramedullary pins in a normograde manner. The patients were then treated as follows: Group 1: with autologous bone marrow aspirate on the day of surgery; Group 2: with autologous bone marrow aspirate on days 0 and 14 post surgery; Group 3: with autologous bone marrow aspirate on days 0, 14 and 28 post surgery; Group 4: 1 ml normal saline was applied on the fracture site. Post-treatment radiographs of the fractures were taken on weeks 1, 2, 4, 7 and 10. The rate of healing was compared using radiographic union scale for tibia scores. The results showed a significant difference (p < .05) in the healing of the treated groups and the control at week 7 post surgery. There was however no significant (p > .05) difference in the healing of the fractures with single and the multiple applications.http://dx.doi.org/10.1080/09712119.2017.1408466Bone marrow aspiratesingle applicationmultiple applicationsfracture healingdog |
| spellingShingle | Theophilus Okafor Nnaji Innocent Nwaogu Nnenna Ugwu Chioma Onyenekwe Evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of Nigerian indigenous dogs Journal of Applied Animal Research Bone marrow aspirate single application multiple applications fracture healing dog |
| title | Evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of Nigerian indigenous dogs |
| title_full | Evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of Nigerian indigenous dogs |
| title_fullStr | Evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of Nigerian indigenous dogs |
| title_full_unstemmed | Evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of Nigerian indigenous dogs |
| title_short | Evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of Nigerian indigenous dogs |
| title_sort | evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of nigerian indigenous dogs |
| topic | Bone marrow aspirate single application multiple applications fracture healing dog |
| url | http://dx.doi.org/10.1080/09712119.2017.1408466 |
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