Therapeutic and functional approach for the treatment of patients with bone marrow edema in Rehabilitation Medicine
Bone marrow edema (BME) represents an imaging finding in various diseases, and often causes pain and significant dysfunction. Although few data are available about its etiology, several hypotheses have been developed to explain the pathogenetic mechanisms of BME. Increased intravascular pressure a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Verduci Editore
2020-09-01
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| Series: | Beyond Rheumatology |
| Subjects: | |
| Online Access: | https://www.beyond-rheumatology.org/wp-content/uploads/sites/10/2022/05/br-2-2-39.pdf |
| _version_ | 1797831378902974464 |
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| author | Loredana Cavalli Giuseppe Falcone Tiziana Cavalli Pietro Pasquetti |
| author_facet | Loredana Cavalli Giuseppe Falcone Tiziana Cavalli Pietro Pasquetti |
| author_sort | Loredana Cavalli |
| collection | DOAJ |
| description | Bone marrow edema (BME) represents an imaging finding in various diseases, and often causes pain and significant dysfunction.
Although few data are available about its etiology, several hypotheses have been developed to explain the pathogenetic mechanisms of BME.
Increased intravascular pressure and capillary leakage within the bone marrow would lead to nerve irritation, causing pain. Bone turnover would increase locally, due to proinflammatory molecules driven by the primary cause of BME (trauma, ischemia, arthritis, .). In addition to imaging findings, the clinical evaluation of a subject affected by BME should rely on an accurate functional assessment, as this condition often leads to transient disability. As regards therapeutic approaches, recent research works have reported benefits from the extracorporeal shock wave treatment (ESWT) and above all bisphosphonates.
A deeper knowledge of the pathophysiological bases of the BME combined with the classic physiatric approach can allow to select the subjects affected by BME who can benefit from therapies such as bisphosphonates and ESWT, and evaluate their clinical and functional effects. |
| first_indexed | 2024-04-09T13:51:23Z |
| format | Article |
| id | doaj.art-1d60e76094a64b1181e2909a7e48868f |
| institution | Directory Open Access Journal |
| issn | 2612-5110 |
| language | English |
| last_indexed | 2024-04-09T13:51:23Z |
| publishDate | 2020-09-01 |
| publisher | Verduci Editore |
| record_format | Article |
| series | Beyond Rheumatology |
| spelling | doaj.art-1d60e76094a64b1181e2909a7e48868f2023-05-08T14:41:24ZengVerduci EditoreBeyond Rheumatology2612-51102020-09-01210.4081/br.2020.39275Therapeutic and functional approach for the treatment of patients with bone marrow edema in Rehabilitation MedicineLoredana Cavalli0Giuseppe Falcone1Tiziana Cavalli2Pietro Pasquetti3Società Italiana G.U.I.D.A., Azienda Ospedaliero-Universitaria Careggi, Firenze, ASST Carlo Poma, Mantova, Italy, Azienda Ospedaliero-Universitaria Careggi, Firenze, Bone marrow edema (BME) represents an imaging finding in various diseases, and often causes pain and significant dysfunction. Although few data are available about its etiology, several hypotheses have been developed to explain the pathogenetic mechanisms of BME. Increased intravascular pressure and capillary leakage within the bone marrow would lead to nerve irritation, causing pain. Bone turnover would increase locally, due to proinflammatory molecules driven by the primary cause of BME (trauma, ischemia, arthritis, .). In addition to imaging findings, the clinical evaluation of a subject affected by BME should rely on an accurate functional assessment, as this condition often leads to transient disability. As regards therapeutic approaches, recent research works have reported benefits from the extracorporeal shock wave treatment (ESWT) and above all bisphosphonates. A deeper knowledge of the pathophysiological bases of the BME combined with the classic physiatric approach can allow to select the subjects affected by BME who can benefit from therapies such as bisphosphonates and ESWT, and evaluate their clinical and functional effects.https://www.beyond-rheumatology.org/wp-content/uploads/sites/10/2022/05/br-2-2-39.pdfbone marrow edemabisphosphonatesalgodystrophypain |
| spellingShingle | Loredana Cavalli Giuseppe Falcone Tiziana Cavalli Pietro Pasquetti Therapeutic and functional approach for the treatment of patients with bone marrow edema in Rehabilitation Medicine Beyond Rheumatology bone marrow edema bisphosphonates algodystrophy pain |
| title | Therapeutic and functional approach for the treatment of patients with bone marrow edema in Rehabilitation Medicine |
| title_full | Therapeutic and functional approach for the treatment of patients with bone marrow edema in Rehabilitation Medicine |
| title_fullStr | Therapeutic and functional approach for the treatment of patients with bone marrow edema in Rehabilitation Medicine |
| title_full_unstemmed | Therapeutic and functional approach for the treatment of patients with bone marrow edema in Rehabilitation Medicine |
| title_short | Therapeutic and functional approach for the treatment of patients with bone marrow edema in Rehabilitation Medicine |
| title_sort | therapeutic and functional approach for the treatment of patients with bone marrow edema in rehabilitation medicine |
| topic | bone marrow edema bisphosphonates algodystrophy pain |
| url | https://www.beyond-rheumatology.org/wp-content/uploads/sites/10/2022/05/br-2-2-39.pdf |
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