A rare case of adverse drug reaction and drug interaction in a human immunodeficiency virus patient
We are reporting a case of rifabutin-induced uveitis in a woman with human immunodeficiency virus (HIV)-tuberculosis (TB) coinfection involving the right hip. Identifying the culprit drug and tailoring the appropriate regimen was a challenge to the clinicians. We described the clinical features, oph...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Clinical and Scientific Research |
| Subjects: | |
| Online Access: | http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2021;volume=10;issue=4;spage=249;epage=251;aulast=Kavya |
| _version_ | 1818509396743815168 |
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| author | Kaza Kavya M V S. Subbalaxmi Mutnuru Phani Chakravarty Soanker Radhika Mallika Goyal |
| author_facet | Kaza Kavya M V S. Subbalaxmi Mutnuru Phani Chakravarty Soanker Radhika Mallika Goyal |
| author_sort | Kaza Kavya |
| collection | DOAJ |
| description | We are reporting a case of rifabutin-induced uveitis in a woman with human immunodeficiency virus (HIV)-tuberculosis (TB) coinfection involving the right hip. Identifying the culprit drug and tailoring the appropriate regimen was a challenge to the clinicians. We described the clinical features, ophthalmological findings, laboratory findings and radiological findings in skeletal TB and follow-up in a woman with HIV-TB coinfection. Improvement of vision on stopping rifabutin with rifampicin confirmed our diagnosis. This case highlights about adverse drug reactions and drug interactions in case of HIV and TB coinfection. Patients receiving therapy with combinations of any of these agents should be warned about signs and symptoms of uveitis and monitored closely for the development of rifabutin toxicity. |
| first_indexed | 2024-12-10T22:44:57Z |
| format | Article |
| id | doaj.art-1d6269d47dad40a58b2bf5df08449fcf |
| institution | Directory Open Access Journal |
| issn | 2277-5706 2277-8357 |
| language | English |
| last_indexed | 2024-12-10T22:44:57Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Clinical and Scientific Research |
| spelling | doaj.art-1d6269d47dad40a58b2bf5df08449fcf2022-12-22T01:30:36ZengWolters Kluwer Medknow PublicationsJournal of Clinical and Scientific Research2277-57062277-83572021-01-0110424925110.4103/JCSR.JCSR_6_20A rare case of adverse drug reaction and drug interaction in a human immunodeficiency virus patientKaza KavyaM V S. SubbalaxmiMutnuru Phani ChakravartySoanker RadhikaMallika GoyalWe are reporting a case of rifabutin-induced uveitis in a woman with human immunodeficiency virus (HIV)-tuberculosis (TB) coinfection involving the right hip. Identifying the culprit drug and tailoring the appropriate regimen was a challenge to the clinicians. We described the clinical features, ophthalmological findings, laboratory findings and radiological findings in skeletal TB and follow-up in a woman with HIV-TB coinfection. Improvement of vision on stopping rifabutin with rifampicin confirmed our diagnosis. This case highlights about adverse drug reactions and drug interactions in case of HIV and TB coinfection. Patients receiving therapy with combinations of any of these agents should be warned about signs and symptoms of uveitis and monitored closely for the development of rifabutin toxicity.http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2021;volume=10;issue=4;spage=249;epage=251;aulast=Kavyahuman immunodeficiency virusrifabutintuberculosisuveitis |
| spellingShingle | Kaza Kavya M V S. Subbalaxmi Mutnuru Phani Chakravarty Soanker Radhika Mallika Goyal A rare case of adverse drug reaction and drug interaction in a human immunodeficiency virus patient Journal of Clinical and Scientific Research human immunodeficiency virus rifabutin tuberculosis uveitis |
| title | A rare case of adverse drug reaction and drug interaction in a human immunodeficiency virus patient |
| title_full | A rare case of adverse drug reaction and drug interaction in a human immunodeficiency virus patient |
| title_fullStr | A rare case of adverse drug reaction and drug interaction in a human immunodeficiency virus patient |
| title_full_unstemmed | A rare case of adverse drug reaction and drug interaction in a human immunodeficiency virus patient |
| title_short | A rare case of adverse drug reaction and drug interaction in a human immunodeficiency virus patient |
| title_sort | rare case of adverse drug reaction and drug interaction in a human immunodeficiency virus patient |
| topic | human immunodeficiency virus rifabutin tuberculosis uveitis |
| url | http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2021;volume=10;issue=4;spage=249;epage=251;aulast=Kavya |
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