Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit

Background: Hyperglycemia is an independent risk factor for mortality in neonatal intensive care units (NICU).Herein, we aimed to investigate the relationship of hyperglycemia duration with mortality and ventilator dependence in infants admitted to NICU.Methods: In this original retrospective study,...

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Main Authors: Vahideh Banna Zadeh, Gholamreza Khademi, Forugh Rakhshanizadeh, Bahareh Imani, Nooshin Abdollahpour, Majid Sezavar
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-06-01
Series:Iranian Journal of Neonatology
Subjects:
Online Access:http://ijn.mums.ac.ir/article_8920_8ed18328d0a9c0e9a32b7d3efb768577.pdf
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author Vahideh Banna Zadeh
Gholamreza Khademi
Forugh Rakhshanizadeh
Bahareh Imani
Nooshin Abdollahpour
Majid Sezavar
author_facet Vahideh Banna Zadeh
Gholamreza Khademi
Forugh Rakhshanizadeh
Bahareh Imani
Nooshin Abdollahpour
Majid Sezavar
author_sort Vahideh Banna Zadeh
collection DOAJ
description Background: Hyperglycemia is an independent risk factor for mortality in neonatal intensive care units (NICU).Herein, we aimed to investigate the relationship of hyperglycemia duration with mortality and ventilator dependence in infants admitted to NICU.Methods: In this original retrospective study, data was collected between October 2015 and December 2015 from NICU of Dr. Sheikh Children’s Hospital in Mashhad, Iran. The studied samples (n=112) were 0-3 month old infants who were admitted to this hospital and were followed up until discharge. Information related to blood sugar was collected based on the samples routinely taken using a glucometer every six hours and were recorded in each patient's blood sugar chart.Results: Of the subjects, 46.4% (n=52) had blood sugar ≥ 126 mg/dl and 53.6% (n=60) had blood sugar ≤ 40-125mg/dl. Mann-Whitney and logistic regression tests were used to analyze the data. In this study, we controlled the effect of confounding variables; a significant association was observed between mortality and duration of hyperglycemia (P=0.002). In addition, a significant association was observed between duration of hyperglycemia and ventilator dependence (P=0.02).Conclusion: Our study showed that the duration of hyperglycemia is positively associated with mortality andventilator dependence in infants admitted to NICU.
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spelling doaj.art-1d645d4caa9442fcb45848081bc0cbf32022-12-21T22:08:33ZengMashhad University of Medical SciencesIranian Journal of Neonatology2251-75102322-21582017-06-0182364310.22038/ijn.2017.89208920Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care UnitVahideh Banna Zadeh0Gholamreza Khademi1Forugh Rakhshanizadeh2Bahareh Imani3Nooshin Abdollahpour4Majid Sezavar5Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Biology, Faculty of Sciences, Young Researchers and Elite Club, Islamic Azad University, Mashhad Branch, Mashhad, IranDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranBackground: Hyperglycemia is an independent risk factor for mortality in neonatal intensive care units (NICU).Herein, we aimed to investigate the relationship of hyperglycemia duration with mortality and ventilator dependence in infants admitted to NICU.Methods: In this original retrospective study, data was collected between October 2015 and December 2015 from NICU of Dr. Sheikh Children’s Hospital in Mashhad, Iran. The studied samples (n=112) were 0-3 month old infants who were admitted to this hospital and were followed up until discharge. Information related to blood sugar was collected based on the samples routinely taken using a glucometer every six hours and were recorded in each patient's blood sugar chart.Results: Of the subjects, 46.4% (n=52) had blood sugar ≥ 126 mg/dl and 53.6% (n=60) had blood sugar ≤ 40-125mg/dl. Mann-Whitney and logistic regression tests were used to analyze the data. In this study, we controlled the effect of confounding variables; a significant association was observed between mortality and duration of hyperglycemia (P=0.002). In addition, a significant association was observed between duration of hyperglycemia and ventilator dependence (P=0.02).Conclusion: Our study showed that the duration of hyperglycemia is positively associated with mortality andventilator dependence in infants admitted to NICU.http://ijn.mums.ac.ir/article_8920_8ed18328d0a9c0e9a32b7d3efb768577.pdfDuration of hyperglycemiaHyperglycemiaInfantsLength of stayMortalityNeonatal intensive care unitventilation
spellingShingle Vahideh Banna Zadeh
Gholamreza Khademi
Forugh Rakhshanizadeh
Bahareh Imani
Nooshin Abdollahpour
Majid Sezavar
Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit
Iranian Journal of Neonatology
Duration of hyperglycemia
Hyperglycemia
Infants
Length of stay
Mortality
Neonatal intensive care unit
ventilation
title Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit
title_full Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit
title_fullStr Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit
title_full_unstemmed Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit
title_short Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit
title_sort impact of hyperglycemia duration on mortality and ventilator dependence in neonatal intensive care unit
topic Duration of hyperglycemia
Hyperglycemia
Infants
Length of stay
Mortality
Neonatal intensive care unit
ventilation
url http://ijn.mums.ac.ir/article_8920_8ed18328d0a9c0e9a32b7d3efb768577.pdf
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