Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit
Background: Hyperglycemia is an independent risk factor for mortality in neonatal intensive care units (NICU).Herein, we aimed to investigate the relationship of hyperglycemia duration with mortality and ventilator dependence in infants admitted to NICU.Methods: In this original retrospective study,...
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Mashhad University of Medical Sciences
2017-06-01
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Series: | Iranian Journal of Neonatology |
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Online Access: | http://ijn.mums.ac.ir/article_8920_8ed18328d0a9c0e9a32b7d3efb768577.pdf |
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author | Vahideh Banna Zadeh Gholamreza Khademi Forugh Rakhshanizadeh Bahareh Imani Nooshin Abdollahpour Majid Sezavar |
author_facet | Vahideh Banna Zadeh Gholamreza Khademi Forugh Rakhshanizadeh Bahareh Imani Nooshin Abdollahpour Majid Sezavar |
author_sort | Vahideh Banna Zadeh |
collection | DOAJ |
description | Background: Hyperglycemia is an independent risk factor for mortality in neonatal intensive care units (NICU).Herein, we aimed to investigate the relationship of hyperglycemia duration with mortality and ventilator dependence in infants admitted to NICU.Methods: In this original retrospective study, data was collected between October 2015 and December 2015 from NICU of Dr. Sheikh Children’s Hospital in Mashhad, Iran. The studied samples (n=112) were 0-3 month old infants who were admitted to this hospital and were followed up until discharge. Information related to blood sugar was collected based on the samples routinely taken using a glucometer every six hours and were recorded in each patient's blood sugar chart.Results: Of the subjects, 46.4% (n=52) had blood sugar ≥ 126 mg/dl and 53.6% (n=60) had blood sugar ≤ 40-125mg/dl. Mann-Whitney and logistic regression tests were used to analyze the data. In this study, we controlled the effect of confounding variables; a significant association was observed between mortality and duration of hyperglycemia (P=0.002). In addition, a significant association was observed between duration of hyperglycemia and ventilator dependence (P=0.02).Conclusion: Our study showed that the duration of hyperglycemia is positively associated with mortality andventilator dependence in infants admitted to NICU. |
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institution | Directory Open Access Journal |
issn | 2251-7510 2322-2158 |
language | English |
last_indexed | 2024-12-17T01:32:05Z |
publishDate | 2017-06-01 |
publisher | Mashhad University of Medical Sciences |
record_format | Article |
series | Iranian Journal of Neonatology |
spelling | doaj.art-1d645d4caa9442fcb45848081bc0cbf32022-12-21T22:08:33ZengMashhad University of Medical SciencesIranian Journal of Neonatology2251-75102322-21582017-06-0182364310.22038/ijn.2017.89208920Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care UnitVahideh Banna Zadeh0Gholamreza Khademi1Forugh Rakhshanizadeh2Bahareh Imani3Nooshin Abdollahpour4Majid Sezavar5Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Biology, Faculty of Sciences, Young Researchers and Elite Club, Islamic Azad University, Mashhad Branch, Mashhad, IranDepartment of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranBackground: Hyperglycemia is an independent risk factor for mortality in neonatal intensive care units (NICU).Herein, we aimed to investigate the relationship of hyperglycemia duration with mortality and ventilator dependence in infants admitted to NICU.Methods: In this original retrospective study, data was collected between October 2015 and December 2015 from NICU of Dr. Sheikh Children’s Hospital in Mashhad, Iran. The studied samples (n=112) were 0-3 month old infants who were admitted to this hospital and were followed up until discharge. Information related to blood sugar was collected based on the samples routinely taken using a glucometer every six hours and were recorded in each patient's blood sugar chart.Results: Of the subjects, 46.4% (n=52) had blood sugar ≥ 126 mg/dl and 53.6% (n=60) had blood sugar ≤ 40-125mg/dl. Mann-Whitney and logistic regression tests were used to analyze the data. In this study, we controlled the effect of confounding variables; a significant association was observed between mortality and duration of hyperglycemia (P=0.002). In addition, a significant association was observed between duration of hyperglycemia and ventilator dependence (P=0.02).Conclusion: Our study showed that the duration of hyperglycemia is positively associated with mortality andventilator dependence in infants admitted to NICU.http://ijn.mums.ac.ir/article_8920_8ed18328d0a9c0e9a32b7d3efb768577.pdfDuration of hyperglycemiaHyperglycemiaInfantsLength of stayMortalityNeonatal intensive care unitventilation |
spellingShingle | Vahideh Banna Zadeh Gholamreza Khademi Forugh Rakhshanizadeh Bahareh Imani Nooshin Abdollahpour Majid Sezavar Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit Iranian Journal of Neonatology Duration of hyperglycemia Hyperglycemia Infants Length of stay Mortality Neonatal intensive care unit ventilation |
title | Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit |
title_full | Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit |
title_fullStr | Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit |
title_full_unstemmed | Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit |
title_short | Impact of Hyperglycemia Duration on Mortality and Ventilator Dependence in Neonatal Intensive Care Unit |
title_sort | impact of hyperglycemia duration on mortality and ventilator dependence in neonatal intensive care unit |
topic | Duration of hyperglycemia Hyperglycemia Infants Length of stay Mortality Neonatal intensive care unit ventilation |
url | http://ijn.mums.ac.ir/article_8920_8ed18328d0a9c0e9a32b7d3efb768577.pdf |
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