The clinical efficacy and safety of acupuncture intervention on cancer-related insomnia: A systematic review and meta-analysis
ObjectiveTo evaluate the efficacy and safety of acupuncture in treating symptoms for Cancer-related Insomnia(CRI) patients.MethodsSeven databases were searched from the time of database establishment to 31 March 2022. Randomized Controlled Trials (RCTs) on acupuncture intervention for CRI were colle...
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| Format: | Article |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2022.1026759/full |
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| author | HaiXin Yu CaiYun Liu Bo Chen Bo Chen JingBo Zhai DongSheng Ba Zheng Zhu NingCen Li PeiYong Loh AoXiang Chen Bin Wang Yi Guo Yi Guo YangYang Liu YangYang Liu ZeLin Chen ZeLin Chen |
| author_facet | HaiXin Yu CaiYun Liu Bo Chen Bo Chen JingBo Zhai DongSheng Ba Zheng Zhu NingCen Li PeiYong Loh AoXiang Chen Bin Wang Yi Guo Yi Guo YangYang Liu YangYang Liu ZeLin Chen ZeLin Chen |
| author_sort | HaiXin Yu |
| collection | DOAJ |
| description | ObjectiveTo evaluate the efficacy and safety of acupuncture in treating symptoms for Cancer-related Insomnia(CRI) patients.MethodsSeven databases were searched from the time of database establishment to 31 March 2022. Randomized Controlled Trials (RCTs) on acupuncture intervention for CRI were collected. Literature screening and data extraction were performed independently by two researchers. Meta-analysis was performed using RevMan 5.4 software.ResultsA total of 13 articles with 1,109 participants were included. Five hundred and seventeen in the treatment group and 592 in the control group. Ten of the RCTs used the PSQI rating scale and four randomized controlled trials used the ISI rating scale, and the PSQI and ISI were analyzed together as continuous data. The results of the meta-analysis were: MD = −1.83, 95%CI = [−2.71, −0.94], P < 0.0001, indicating a significant improvement in PSQI scores in patients with CRI by acupuncture intervention; MD = 0.79, 95%CI = [−0.46, 2.03], P = 0.22. Acupuncture was not statistically significant on ISI scores for patients with CRI compared to controls, which does not yet indicate that acupuncture is effective for symptoms in patients with CRI. The results of the meta-analysis of the other 4 items using sleep disorder logs as efficacy analysis data were as follow, relative risk RR = 0.47, 95%CI = [0.33, 0.66], P < 0.0001. The difference was statistically significant, indicating that acupuncture can improve the symptoms of CRI patients compared to control group.ConclusionAcupuncture can improve the symptoms of patients with CRI to some extent, but due to the relatively small number and low quality of the included literature in this study, more high-quality clinical trials are needed as supplement the evidences in future.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/. |
| first_indexed | 2024-04-11T05:57:14Z |
| format | Article |
| id | doaj.art-1d6467c9e14149699527e37f5f825088 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-04-11T05:57:14Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-1d6467c9e14149699527e37f5f8250882022-12-22T04:41:50ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2022-12-011610.3389/fnins.2022.10267591026759The clinical efficacy and safety of acupuncture intervention on cancer-related insomnia: A systematic review and meta-analysisHaiXin Yu0CaiYun Liu1Bo Chen2Bo Chen3JingBo Zhai4DongSheng Ba5Zheng Zhu6NingCen Li7PeiYong Loh8AoXiang Chen9Bin Wang10Yi Guo11Yi Guo12YangYang Liu13YangYang Liu14ZeLin Chen15ZeLin Chen16Department of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaDepartment of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaDepartment of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaEvidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaDepartment of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaDepartment of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaDepartment of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaDepartment of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, ChinaNational Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, ChinaDepartment of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaDepartment of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaDepartment of Acu-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaAcupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaObjectiveTo evaluate the efficacy and safety of acupuncture in treating symptoms for Cancer-related Insomnia(CRI) patients.MethodsSeven databases were searched from the time of database establishment to 31 March 2022. Randomized Controlled Trials (RCTs) on acupuncture intervention for CRI were collected. Literature screening and data extraction were performed independently by two researchers. Meta-analysis was performed using RevMan 5.4 software.ResultsA total of 13 articles with 1,109 participants were included. Five hundred and seventeen in the treatment group and 592 in the control group. Ten of the RCTs used the PSQI rating scale and four randomized controlled trials used the ISI rating scale, and the PSQI and ISI were analyzed together as continuous data. The results of the meta-analysis were: MD = −1.83, 95%CI = [−2.71, −0.94], P < 0.0001, indicating a significant improvement in PSQI scores in patients with CRI by acupuncture intervention; MD = 0.79, 95%CI = [−0.46, 2.03], P = 0.22. Acupuncture was not statistically significant on ISI scores for patients with CRI compared to controls, which does not yet indicate that acupuncture is effective for symptoms in patients with CRI. The results of the meta-analysis of the other 4 items using sleep disorder logs as efficacy analysis data were as follow, relative risk RR = 0.47, 95%CI = [0.33, 0.66], P < 0.0001. The difference was statistically significant, indicating that acupuncture can improve the symptoms of CRI patients compared to control group.ConclusionAcupuncture can improve the symptoms of patients with CRI to some extent, but due to the relatively small number and low quality of the included literature in this study, more high-quality clinical trials are needed as supplement the evidences in future.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/.https://www.frontiersin.org/articles/10.3389/fnins.2022.1026759/fullacupuncturecancer-related insomniasystematic reviewmeta-analysisPSQIefficacy |
| spellingShingle | HaiXin Yu CaiYun Liu Bo Chen Bo Chen JingBo Zhai DongSheng Ba Zheng Zhu NingCen Li PeiYong Loh AoXiang Chen Bin Wang Yi Guo Yi Guo YangYang Liu YangYang Liu ZeLin Chen ZeLin Chen The clinical efficacy and safety of acupuncture intervention on cancer-related insomnia: A systematic review and meta-analysis Frontiers in Neuroscience acupuncture cancer-related insomnia systematic review meta-analysis PSQI efficacy |
| title | The clinical efficacy and safety of acupuncture intervention on cancer-related insomnia: A systematic review and meta-analysis |
| title_full | The clinical efficacy and safety of acupuncture intervention on cancer-related insomnia: A systematic review and meta-analysis |
| title_fullStr | The clinical efficacy and safety of acupuncture intervention on cancer-related insomnia: A systematic review and meta-analysis |
| title_full_unstemmed | The clinical efficacy and safety of acupuncture intervention on cancer-related insomnia: A systematic review and meta-analysis |
| title_short | The clinical efficacy and safety of acupuncture intervention on cancer-related insomnia: A systematic review and meta-analysis |
| title_sort | clinical efficacy and safety of acupuncture intervention on cancer related insomnia a systematic review and meta analysis |
| topic | acupuncture cancer-related insomnia systematic review meta-analysis PSQI efficacy |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2022.1026759/full |
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