DNA adenine methylation is required to replicate both Vibrio cholerae chromosomes once per cell cycle.

DNA adenine methylation is widely used to control many DNA transactions, including replication. In Escherichia coli, methylation serves to silence newly synthesized (hemimethylated) sister origins. SeqA, a protein that binds to hemimethylated DNA, mediates the silencing, and this is necessary to res...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Gaëlle Demarre, Dhruba K Chattoraj
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Public Library of Science (PLoS) 2010-05-01
Цуврал:PLoS Genetics
Онлайн хандалт:http://europepmc.org/articles/PMC2865523?pdf=render