From Body Monitoring to Biomolecular Sensing: Current Progress and Future Perspectives of Triboelectric Nanogenerators in Point-of-Care Diagnostics
In the constantly evolving field of medical diagnostics, triboelectric nanogenerators (TENGs) stand out as a groundbreaking innovation for simultaneously harnessing mechanical energy from micromovements and sensing stimuli from both the human body and the ambient environment. This advancement dimini...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/24/2/511 |
| _version_ | 1797339391816892416 |
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| author | Zequan Zhao Yajun Mi Hafeez Ur Rehman Enqi Sun Xia Cao Ning Wang |
| author_facet | Zequan Zhao Yajun Mi Hafeez Ur Rehman Enqi Sun Xia Cao Ning Wang |
| author_sort | Zequan Zhao |
| collection | DOAJ |
| description | In the constantly evolving field of medical diagnostics, triboelectric nanogenerators (TENGs) stand out as a groundbreaking innovation for simultaneously harnessing mechanical energy from micromovements and sensing stimuli from both the human body and the ambient environment. This advancement diminishes the dependence of biosensors on external power sources and paves the way for the application of TENGs in self-powered medical devices, especially in the realm of point-of-care diagnostics. In this review, we delve into the functionality of TENGs in point-of-care diagnostics. First, from the basic principle of how TENGs effectively transform subtle physical movements into electrical energy, thereby promoting the development of self-powered biosensors and medical devices that are particularly advantageous for real-time biological monitoring. Then, the adaptable design of TENGs that facilitate customization to meet individual patient needs is introduced, with a focus on their biocompatibility and safety in medical applications. Our in-depth analysis also covers TENG-based biosensor designs moving toward exceptional sensitivity and specificity in biomarker detection, for accurate and efficient diagnoses. Challenges and future prospects such as the integration of TENGs into wearable and implantable devices are also discussed. We aim for this review to illuminate the burgeoning field of TENG-based intelligent devices for continuous, real-time health monitoring; and to inspire further innovation in this captivating area of research that is in line with patient-centered healthcare. |
| first_indexed | 2024-03-08T09:46:18Z |
| format | Article |
| id | doaj.art-1d6d90c73d1141baa806e2b0e59035c4 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-08T09:46:18Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-1d6d90c73d1141baa806e2b0e59035c42024-01-29T14:15:47ZengMDPI AGSensors1424-82202024-01-0124251110.3390/s24020511From Body Monitoring to Biomolecular Sensing: Current Progress and Future Perspectives of Triboelectric Nanogenerators in Point-of-Care DiagnosticsZequan Zhao0Yajun Mi1Hafeez Ur Rehman2Enqi Sun3Xia Cao4Ning Wang5Center for Green Innovation, School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, ChinaCenter for Green Innovation, School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, ChinaCenter for Green Innovation, School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, ChinaCenter for Green Innovation, School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, ChinaBeijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, ChinaCenter for Green Innovation, School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100083, ChinaIn the constantly evolving field of medical diagnostics, triboelectric nanogenerators (TENGs) stand out as a groundbreaking innovation for simultaneously harnessing mechanical energy from micromovements and sensing stimuli from both the human body and the ambient environment. This advancement diminishes the dependence of biosensors on external power sources and paves the way for the application of TENGs in self-powered medical devices, especially in the realm of point-of-care diagnostics. In this review, we delve into the functionality of TENGs in point-of-care diagnostics. First, from the basic principle of how TENGs effectively transform subtle physical movements into electrical energy, thereby promoting the development of self-powered biosensors and medical devices that are particularly advantageous for real-time biological monitoring. Then, the adaptable design of TENGs that facilitate customization to meet individual patient needs is introduced, with a focus on their biocompatibility and safety in medical applications. Our in-depth analysis also covers TENG-based biosensor designs moving toward exceptional sensitivity and specificity in biomarker detection, for accurate and efficient diagnoses. Challenges and future prospects such as the integration of TENGs into wearable and implantable devices are also discussed. We aim for this review to illuminate the burgeoning field of TENG-based intelligent devices for continuous, real-time health monitoring; and to inspire further innovation in this captivating area of research that is in line with patient-centered healthcare.https://www.mdpi.com/1424-8220/24/2/511point-of-care diagnosticstriboelectric nanogeneratorself-powered sensingwearable electronics |
| spellingShingle | Zequan Zhao Yajun Mi Hafeez Ur Rehman Enqi Sun Xia Cao Ning Wang From Body Monitoring to Biomolecular Sensing: Current Progress and Future Perspectives of Triboelectric Nanogenerators in Point-of-Care Diagnostics Sensors point-of-care diagnostics triboelectric nanogenerator self-powered sensing wearable electronics |
| title | From Body Monitoring to Biomolecular Sensing: Current Progress and Future Perspectives of Triboelectric Nanogenerators in Point-of-Care Diagnostics |
| title_full | From Body Monitoring to Biomolecular Sensing: Current Progress and Future Perspectives of Triboelectric Nanogenerators in Point-of-Care Diagnostics |
| title_fullStr | From Body Monitoring to Biomolecular Sensing: Current Progress and Future Perspectives of Triboelectric Nanogenerators in Point-of-Care Diagnostics |
| title_full_unstemmed | From Body Monitoring to Biomolecular Sensing: Current Progress and Future Perspectives of Triboelectric Nanogenerators in Point-of-Care Diagnostics |
| title_short | From Body Monitoring to Biomolecular Sensing: Current Progress and Future Perspectives of Triboelectric Nanogenerators in Point-of-Care Diagnostics |
| title_sort | from body monitoring to biomolecular sensing current progress and future perspectives of triboelectric nanogenerators in point of care diagnostics |
| topic | point-of-care diagnostics triboelectric nanogenerator self-powered sensing wearable electronics |
| url | https://www.mdpi.com/1424-8220/24/2/511 |
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