Treatment of malignant glaucoma with minimal invasive vitrectomy surgery

AIM:To evaluate the efficacy of 25G vitrectomy surgery for malignant glaucoma. <p>METHODS: Thirteen eyes of 11 patients with malignant glaucoma who had a history of primary angle-closure glaucoma were analyzed retrospectively from September 2012 to October 2013 in our hospital. All patients ha...

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Main Authors: Li Meng, Xiao-Dong Han, Yan-Long Li, Min Yang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-09-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2015/9/201509043.pdf
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author Li Meng
Xiao-Dong Han
Yan-Long Li
Min Yang
author_facet Li Meng
Xiao-Dong Han
Yan-Long Li
Min Yang
author_sort Li Meng
collection DOAJ
description AIM:To evaluate the efficacy of 25G vitrectomy surgery for malignant glaucoma. <p>METHODS: Thirteen eyes of 11 patients with malignant glaucoma who had a history of primary angle-closure glaucoma were analyzed retrospectively from September 2012 to October 2013 in our hospital. All patients had undergone a prior surgery of trebeculectomy combined with iridectomy. The pre-operative mean best corrected visual acuity(BCVA)in LogMAR was 0.70±0.13 and the mean intraocular pressure(IOP)was 41.3±12.7mmHg. Corneal edema, ciliary body edema and very shallow anterior chamber with a mean value of 0.69±0.17mm were showed by ultrasound biomicroscopy(UBM). Anterior vitrectomy and posterior capsulotomy were performed with 25G vitrectomy system in all eyes. Seven phakic eyes underwent phacoimulsification combined IOL implantation surgery during vitrectomy.<p>RESULTS: The patients were followed up for 6~18mo with an average of 11.7±5.4mo. BCVA at the last follow-up improved to 0.29±0.08 and the mean IOP was 18.6±3.9mmHg. UBM results showed that ciliary body edema was eliminated, the iris was flattened and the anterior chamber was deepened with a mean depth of 2.48±0.31mm at 1mo after surgery. Postoperative complications included corneal edma, Descemet membrane folds, anterior chamber inflammation, fibrotic exudation, local iris posterior synechia and hypotony(IOP≤5mmHg). One eye had high IOP of 26.4mmHg and required long-term topical antiglaucoma medication to control the IOP≤21mmHg. No complications such as corneal endothelium decompensation, IOL capture, intraocular hemorrhage, infection and uncontrolled IOP were observed. <p>CONCLUSION: 25G vitrectomy is safe and effective for treating malignant glaucoma, controls IOP and reduces complications associated with traditional vitrectomy. Combined vitrectomy with phacoemulsification may improve the success rate and visual function.
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spelling doaj.art-1d6de693474a41cbb0e0c45eed9f3d562022-12-21T23:06:11ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-09-011591645164710.3980/j.issn.1672-5123.2015.9.43Treatment of malignant glaucoma with minimal invasive vitrectomy surgeryLi Meng0Xiao-Dong Han1Yan-Long Li2Min Yang3Xi'an Aier Ancient City Eye Hospital, Xi'an 710014,Shaanxi Province, ChinaXi'an Aier Ancient City Eye Hospital, Xi'an 710014,Shaanxi Province, ChinaXi'an Aier Ancient City Eye Hospital, Xi'an 710014,Shaanxi Province, ChinaXi'an Aier Ancient City Eye Hospital, Xi'an 710014,Shaanxi Province, ChinaAIM:To evaluate the efficacy of 25G vitrectomy surgery for malignant glaucoma. <p>METHODS: Thirteen eyes of 11 patients with malignant glaucoma who had a history of primary angle-closure glaucoma were analyzed retrospectively from September 2012 to October 2013 in our hospital. All patients had undergone a prior surgery of trebeculectomy combined with iridectomy. The pre-operative mean best corrected visual acuity(BCVA)in LogMAR was 0.70±0.13 and the mean intraocular pressure(IOP)was 41.3±12.7mmHg. Corneal edema, ciliary body edema and very shallow anterior chamber with a mean value of 0.69±0.17mm were showed by ultrasound biomicroscopy(UBM). Anterior vitrectomy and posterior capsulotomy were performed with 25G vitrectomy system in all eyes. Seven phakic eyes underwent phacoimulsification combined IOL implantation surgery during vitrectomy.<p>RESULTS: The patients were followed up for 6~18mo with an average of 11.7±5.4mo. BCVA at the last follow-up improved to 0.29±0.08 and the mean IOP was 18.6±3.9mmHg. UBM results showed that ciliary body edema was eliminated, the iris was flattened and the anterior chamber was deepened with a mean depth of 2.48±0.31mm at 1mo after surgery. Postoperative complications included corneal edma, Descemet membrane folds, anterior chamber inflammation, fibrotic exudation, local iris posterior synechia and hypotony(IOP≤5mmHg). One eye had high IOP of 26.4mmHg and required long-term topical antiglaucoma medication to control the IOP≤21mmHg. No complications such as corneal endothelium decompensation, IOL capture, intraocular hemorrhage, infection and uncontrolled IOP were observed. <p>CONCLUSION: 25G vitrectomy is safe and effective for treating malignant glaucoma, controls IOP and reduces complications associated with traditional vitrectomy. Combined vitrectomy with phacoemulsification may improve the success rate and visual function.http://ies.ijo.cn/cn_publish/2015/9/201509043.pdfmalignant glaucoma; vitrectomy
spellingShingle Li Meng
Xiao-Dong Han
Yan-Long Li
Min Yang
Treatment of malignant glaucoma with minimal invasive vitrectomy surgery
Guoji Yanke Zazhi
malignant glaucoma; vitrectomy
title Treatment of malignant glaucoma with minimal invasive vitrectomy surgery
title_full Treatment of malignant glaucoma with minimal invasive vitrectomy surgery
title_fullStr Treatment of malignant glaucoma with minimal invasive vitrectomy surgery
title_full_unstemmed Treatment of malignant glaucoma with minimal invasive vitrectomy surgery
title_short Treatment of malignant glaucoma with minimal invasive vitrectomy surgery
title_sort treatment of malignant glaucoma with minimal invasive vitrectomy surgery
topic malignant glaucoma; vitrectomy
url http://ies.ijo.cn/cn_publish/2015/9/201509043.pdf
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AT xiaodonghan treatmentofmalignantglaucomawithminimalinvasivevitrectomysurgery
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AT minyang treatmentofmalignantglaucomawithminimalinvasivevitrectomysurgery