Naftifine hydrochloride (NH) in the treatment of pityriasis versicolor
Introduction & objectives: The purpose of this study was to demonstrate the efficacy comparability of 1% NH lotion vs. of 1% NH cream (exoderil, Sandoz) in the treatment of pityriasis versicolor. Material & methods. 71 patients with pityriasis versicolor were randomly allocated either to rec...
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| Format: | Article |
| Language: | English |
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State Scientific Center of Dermatovenereology and Cosmetology
2017-08-01
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| Series: | Vestnik Dermatologii i Venerologii |
| Subjects: | |
| Online Access: | https://www.vestnikdv.ru/jour/article/view/232 |
| _version_ | 1797721759940608000 |
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| author | L. P. Kotrekhova A. A. Vashkevich E. N. Tsurupa P. A. Reztsova |
| author_facet | L. P. Kotrekhova A. A. Vashkevich E. N. Tsurupa P. A. Reztsova |
| author_sort | L. P. Kotrekhova |
| collection | DOAJ |
| description | Introduction & objectives: The purpose of this study was to demonstrate the efficacy comparability of 1% NH lotion vs. of 1% NH cream (exoderil, Sandoz) in the treatment of pityriasis versicolor. Material & methods. 71 patients with pityriasis versicolor were randomly allocated either to receive NH lotion once daily (NH lotion group (п = 35, 38.6 years (95% CI [33,7, 43.5]) or NH cream once daily (NH cream group (п = 36, 40.8 years (95% CI [36,6, 45.0]) for 14 days. Mycological evaluations (microscopy and culture) were performed at weeks 2 and 3, inflammation symptoms evaluations were scored at day 3, weeks 2 and 3 after start of the therapy. Overall cure rates assessment included results of mycological, clinical outcomes and safety evaluation. Results. There was no difference between groups in mycological cure rates (94% vs 92%) and inflammation regression (97% vs 97%). Overall cure rate was 91% and 92% of patients in NH lotion and NH cream groups respectively (p = 0,97). Conclusion. 1% NH lotion and 1% NH cream are effective in the treatment of pityriasis versicolor. |
| first_indexed | 2024-03-12T09:37:51Z |
| format | Article |
| id | doaj.art-1d704f020f6a4b0cb2662e131aa25725 |
| institution | Directory Open Access Journal |
| issn | 0042-4609 2313-6294 |
| language | English |
| last_indexed | 2024-03-12T09:37:51Z |
| publishDate | 2017-08-01 |
| publisher | State Scientific Center of Dermatovenereology and Cosmetology |
| record_format | Article |
| series | Vestnik Dermatologii i Venerologii |
| spelling | doaj.art-1d704f020f6a4b0cb2662e131aa257252023-09-02T13:27:31ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942017-08-010210310910.25208/0042-4609-2016-0-2-103-109231Naftifine hydrochloride (NH) in the treatment of pityriasis versicolorL. P. Kotrekhova0A. A. Vashkevich1E. N. Tsurupa2P. A. Reztsova3“North-Western State Medical University named after I.I. Mechnikov”“North-Western State Medical University named after I.I. Mechnikov”“North-Western State Medical University named after I.I. Mechnikov”“North-Western State Medical University named after I.I. Mechnikov”Introduction & objectives: The purpose of this study was to demonstrate the efficacy comparability of 1% NH lotion vs. of 1% NH cream (exoderil, Sandoz) in the treatment of pityriasis versicolor. Material & methods. 71 patients with pityriasis versicolor were randomly allocated either to receive NH lotion once daily (NH lotion group (п = 35, 38.6 years (95% CI [33,7, 43.5]) or NH cream once daily (NH cream group (п = 36, 40.8 years (95% CI [36,6, 45.0]) for 14 days. Mycological evaluations (microscopy and culture) were performed at weeks 2 and 3, inflammation symptoms evaluations were scored at day 3, weeks 2 and 3 after start of the therapy. Overall cure rates assessment included results of mycological, clinical outcomes and safety evaluation. Results. There was no difference between groups in mycological cure rates (94% vs 92%) and inflammation regression (97% vs 97%). Overall cure rate was 91% and 92% of patients in NH lotion and NH cream groups respectively (p = 0,97). Conclusion. 1% NH lotion and 1% NH cream are effective in the treatment of pityriasis versicolor.https://www.vestnikdv.ru/jour/article/view/232отрубевидный лишайнафтифина гидрохлоридэкзодерилpityriasis versicolornaftifine hydrochlorideexoderil |
| spellingShingle | L. P. Kotrekhova A. A. Vashkevich E. N. Tsurupa P. A. Reztsova Naftifine hydrochloride (NH) in the treatment of pityriasis versicolor Vestnik Dermatologii i Venerologii отрубевидный лишай нафтифина гидрохлорид экзодерил pityriasis versicolor naftifine hydrochloride exoderil |
| title | Naftifine hydrochloride (NH) in the treatment of pityriasis versicolor |
| title_full | Naftifine hydrochloride (NH) in the treatment of pityriasis versicolor |
| title_fullStr | Naftifine hydrochloride (NH) in the treatment of pityriasis versicolor |
| title_full_unstemmed | Naftifine hydrochloride (NH) in the treatment of pityriasis versicolor |
| title_short | Naftifine hydrochloride (NH) in the treatment of pityriasis versicolor |
| title_sort | naftifine hydrochloride nh in the treatment of pityriasis versicolor |
| topic | отрубевидный лишай нафтифина гидрохлорид экзодерил pityriasis versicolor naftifine hydrochloride exoderil |
| url | https://www.vestnikdv.ru/jour/article/view/232 |
| work_keys_str_mv | AT lpkotrekhova naftifinehydrochloridenhinthetreatmentofpityriasisversicolor AT aavashkevich naftifinehydrochloridenhinthetreatmentofpityriasisversicolor AT entsurupa naftifinehydrochloridenhinthetreatmentofpityriasisversicolor AT pareztsova naftifinehydrochloridenhinthetreatmentofpityriasisversicolor |