Cellular Origins of EGFR‐Driven Lung Cancer Cells Determine Sensitivity to Therapy

Cellular Origins of EGFR‐Driven Lung Cancer Cells Determine Sensitivity to Therapy

Abstract Targeting the epidermal growth factor receptor (EGFR) with tyrosine kinase inhibitors (TKIs) is one of the major precision medicine treatment options for lung adenocarcinoma. Due to common development of drug resistance to first‐ and second‐generation TKIs, third‐generation inhibitors, incl...

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Bibliographic Details
Main Authors: Fan Chen, Jinpeng Liu, Robert M. Flight, Kassandra J. Naughton, Alexsandr Lukyanchuk, Abigail R. Edgin, Xiulong Song, Haikuo Zhang, Kwok‐Kin Wong, Hunter N. B. Moseley, Chi Wang, Christine F. Brainson
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:Advanced Science
Subjects:
alveolar
bronchiolar
EGFR
lung cancer
organoids
Online Access:https://doi.org/10.1002/advs.202101999

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