Epigenetic, transcriptional, and functional characterization of myeloid cells in familial Mediterranean fever

Epigenetic, transcriptional, and functional characterization of myeloid cells in familial Mediterranean fever

Summary: Familial Mediterranean fever (FMF) is a periodic fever syndrome caused by variation in MEFV. FMF is known for IL-1β dysregulation, but the innate immune landscape of this disease has not been comprehensively described. Therefore, we studied circulating inflammatory proteins, and the functio...

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Bibliographic Details
Main Authors: Rutger J. Röring, Wenchao Li, Ruiqi Liu, Mariolina Bruno, Bowen Zhang, Priya A. Debisarun, Orsolya Gaal, Medeea Badii, Viola Klück, Simone J.C.F.M. Moorlag, Frank van de Veerdonk, Yang Li, Leo A.B. Joosten, Mihai G. Netea
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Health sciences
Immunology
Immune response
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224005777

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