"Cross-Cultural Adaptation Of The Multiple Sclerosis Impact Scale (MSIS-29) For Iranian MS Patients, Evaluation Of Reliability And Validity "

Background and Aim: Measuring the outcome of chronic diseases such as multiple sclerosis is an important factor in assessment of disease impact on different dimensions of quality of life and in evaluation of therapeutic interventions. The aim of this study was to perform the cross-cultural adaptatio...

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Main Authors: P. Ayatollahi, S. Nafissi, M. Eshraghian A. Tarazi
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2006-05-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2604.pdf&manuscript_id=2604
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author P. Ayatollahi
S. Nafissi
M. Eshraghian A. Tarazi
author_facet P. Ayatollahi
S. Nafissi
M. Eshraghian A. Tarazi
author_sort P. Ayatollahi
collection DOAJ
description Background and Aim: Measuring the outcome of chronic diseases such as multiple sclerosis is an important factor in assessment of disease impact on different dimensions of quality of life and in evaluation of therapeutic interventions. The aim of this study was to perform the cross-cultural adaptation of the MSIS-29 which is a MS-specific outcome measure for Iranian patients. Materials and Methods: The Iranian adaptation process of the MSIS-29 included 5 steps. To evaluate psychometric properties of the translated version, the questionnaire was administered to a consecutive sample of 96 patients with clinically definite MS referred to our out-patient clinic. Test-retest reliability was assessed in a sub-sample consisted of 30 patients. These patients completed the questionnaire on two occasions separated by a 7-day interval. The Iranian version of the SF-36 was also administered to this sub-sample in order to evaluate the validity of translated MSIS-29. Results: Statistical analysis indicated that the Persian version of the MSIS-29 had high internal consistency (cronbach’s alpha coefficients > 0.70) and test-retest reliability (intra-class correlation coefficients >0.70) and a good validity. Conclusion: The Persian version of the MSIS-29 is a reliable and valid instrument for measuring MS outcome in Iranian patients. It can be used in clinical trials and cross-sectional studies.
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spelling doaj.art-1d7472f9f6894f0eb19be2def95dcf572022-12-22T03:27:45ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222006-05-016416268"Cross-Cultural Adaptation Of The Multiple Sclerosis Impact Scale (MSIS-29) For Iranian MS Patients, Evaluation Of Reliability And Validity "P. AyatollahiS. NafissiM. Eshraghian A. TaraziBackground and Aim: Measuring the outcome of chronic diseases such as multiple sclerosis is an important factor in assessment of disease impact on different dimensions of quality of life and in evaluation of therapeutic interventions. The aim of this study was to perform the cross-cultural adaptation of the MSIS-29 which is a MS-specific outcome measure for Iranian patients. Materials and Methods: The Iranian adaptation process of the MSIS-29 included 5 steps. To evaluate psychometric properties of the translated version, the questionnaire was administered to a consecutive sample of 96 patients with clinically definite MS referred to our out-patient clinic. Test-retest reliability was assessed in a sub-sample consisted of 30 patients. These patients completed the questionnaire on two occasions separated by a 7-day interval. The Iranian version of the SF-36 was also administered to this sub-sample in order to evaluate the validity of translated MSIS-29. Results: Statistical analysis indicated that the Persian version of the MSIS-29 had high internal consistency (cronbach’s alpha coefficients > 0.70) and test-retest reliability (intra-class correlation coefficients >0.70) and a good validity. Conclusion: The Persian version of the MSIS-29 is a reliable and valid instrument for measuring MS outcome in Iranian patients. It can be used in clinical trials and cross-sectional studies.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2604.pdf&manuscript_id=2604MSIS-29 questionnairecross-cultural adaptation
spellingShingle P. Ayatollahi
S. Nafissi
M. Eshraghian A. Tarazi
"Cross-Cultural Adaptation Of The Multiple Sclerosis Impact Scale (MSIS-29) For Iranian MS Patients, Evaluation Of Reliability And Validity "
Tehran University Medical Journal
MSIS-29 questionnaire
cross-cultural adaptation
title "Cross-Cultural Adaptation Of The Multiple Sclerosis Impact Scale (MSIS-29) For Iranian MS Patients, Evaluation Of Reliability And Validity "
title_full "Cross-Cultural Adaptation Of The Multiple Sclerosis Impact Scale (MSIS-29) For Iranian MS Patients, Evaluation Of Reliability And Validity "
title_fullStr "Cross-Cultural Adaptation Of The Multiple Sclerosis Impact Scale (MSIS-29) For Iranian MS Patients, Evaluation Of Reliability And Validity "
title_full_unstemmed "Cross-Cultural Adaptation Of The Multiple Sclerosis Impact Scale (MSIS-29) For Iranian MS Patients, Evaluation Of Reliability And Validity "
title_short "Cross-Cultural Adaptation Of The Multiple Sclerosis Impact Scale (MSIS-29) For Iranian MS Patients, Evaluation Of Reliability And Validity "
title_sort cross cultural adaptation of the multiple sclerosis impact scale msis 29 for iranian ms patients evaluation of reliability and validity
topic MSIS-29 questionnaire
cross-cultural adaptation
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2604.pdf&manuscript_id=2604
work_keys_str_mv AT payatollahi crossculturaladaptationofthemultiplesclerosisimpactscalemsis29foriranianmspatientsevaluationofreliabilityandvalidity
AT snafissi crossculturaladaptationofthemultiplesclerosisimpactscalemsis29foriranianmspatientsevaluationofreliabilityandvalidity
AT meshraghianatarazi crossculturaladaptationofthemultiplesclerosisimpactscalemsis29foriranianmspatientsevaluationofreliabilityandvalidity