The role of invasive and non-invasive imaging technologies and calcium modification therapies in the evaluation and management of coronary artery calcifications

The treatment of coronary artery disease (CAD) has advanced significantly in recent years due to improvements in medical therapy and percutaneous or surgical revascularization. However, a persistent obstacle in the percutaneous management of CAD is coronary artery calcification (CAC), which portends...

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Main Authors: Samuel B. Wopperer, Rafail Kotronias, Federico Marin, Stefano Benenati, Francesco Della Mora, Leonardo Portolan, Adrian P. Banning, Giovanni Luigi De Maria
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1133510/full
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author Samuel B. Wopperer
Rafail Kotronias
Federico Marin
Stefano Benenati
Francesco Della Mora
Francesco Della Mora
Leonardo Portolan
Adrian P. Banning
Giovanni Luigi De Maria
author_facet Samuel B. Wopperer
Rafail Kotronias
Federico Marin
Stefano Benenati
Francesco Della Mora
Francesco Della Mora
Leonardo Portolan
Adrian P. Banning
Giovanni Luigi De Maria
author_sort Samuel B. Wopperer
collection DOAJ
description The treatment of coronary artery disease (CAD) has advanced significantly in recent years due to improvements in medical therapy and percutaneous or surgical revascularization. However, a persistent obstacle in the percutaneous management of CAD is coronary artery calcification (CAC), which portends to higher rates of procedural challenges, post-intervention complications, and overall poor prognosis. With the advent of novel multimodality imaging technologies spanning from intravascular ultrasound to optical coherence tomography to coronary computed tomography angiography combined with advances in calcium debulking and modification techniques, CACs are now targets for intervention with growing success. This review will summarize the most recent developments in the diagnosis and characterization of CAC, offer a comparison of the aforementioned imaging technologies including which ones are most suitable for specific clinical presentations, and review the CAC modifying therapies currently available.
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spelling doaj.art-1d758676019842efb69c508e91ff50a92023-04-06T06:17:38ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-04-011010.3389/fcvm.2023.11335101133510The role of invasive and non-invasive imaging technologies and calcium modification therapies in the evaluation and management of coronary artery calcificationsSamuel B. Wopperer0Rafail Kotronias1Federico Marin2Stefano Benenati3Francesco Della Mora4Francesco Della Mora5Leonardo Portolan6Adrian P. Banning7Giovanni Luigi De Maria8Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United StatesOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals, NHS Foundation Trust, Oxford, United KingdomOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals, NHS Foundation Trust, Oxford, United KingdomOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals, NHS Foundation Trust, Oxford, United KingdomOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals, NHS Foundation Trust, Oxford, United KingdomDivision of Cardiology, Department of Medicine, University of Verona, Verona, ItalyDivision of Cardiology, Department of Medicine, University of Verona, Verona, ItalyOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals, NHS Foundation Trust, Oxford, United KingdomOxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals, NHS Foundation Trust, Oxford, United KingdomThe treatment of coronary artery disease (CAD) has advanced significantly in recent years due to improvements in medical therapy and percutaneous or surgical revascularization. However, a persistent obstacle in the percutaneous management of CAD is coronary artery calcification (CAC), which portends to higher rates of procedural challenges, post-intervention complications, and overall poor prognosis. With the advent of novel multimodality imaging technologies spanning from intravascular ultrasound to optical coherence tomography to coronary computed tomography angiography combined with advances in calcium debulking and modification techniques, CACs are now targets for intervention with growing success. This review will summarize the most recent developments in the diagnosis and characterization of CAC, offer a comparison of the aforementioned imaging technologies including which ones are most suitable for specific clinical presentations, and review the CAC modifying therapies currently available.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1133510/fullnon-invasiveinvasivecoronarycalciumimaging
spellingShingle Samuel B. Wopperer
Rafail Kotronias
Federico Marin
Stefano Benenati
Francesco Della Mora
Francesco Della Mora
Leonardo Portolan
Adrian P. Banning
Giovanni Luigi De Maria
The role of invasive and non-invasive imaging technologies and calcium modification therapies in the evaluation and management of coronary artery calcifications
Frontiers in Cardiovascular Medicine
non-invasive
invasive
coronary
calcium
imaging
title The role of invasive and non-invasive imaging technologies and calcium modification therapies in the evaluation and management of coronary artery calcifications
title_full The role of invasive and non-invasive imaging technologies and calcium modification therapies in the evaluation and management of coronary artery calcifications
title_fullStr The role of invasive and non-invasive imaging technologies and calcium modification therapies in the evaluation and management of coronary artery calcifications
title_full_unstemmed The role of invasive and non-invasive imaging technologies and calcium modification therapies in the evaluation and management of coronary artery calcifications
title_short The role of invasive and non-invasive imaging technologies and calcium modification therapies in the evaluation and management of coronary artery calcifications
title_sort role of invasive and non invasive imaging technologies and calcium modification therapies in the evaluation and management of coronary artery calcifications
topic non-invasive
invasive
coronary
calcium
imaging
url https://www.frontiersin.org/articles/10.3389/fcvm.2023.1133510/full
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