Mesenchymal stem cell-derived extracellular vesicles protect against abdominal aortic aneurysm formation by inhibiting NET-induced ferroptosis

Abstract Neutrophil extracellular traps (NETs) play an important role in abdominal aortic aneurysm (AAA) formation; however, the underlying molecular mechanisms remain unclear. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) may exert therapeutic effects on AAA through their immunomod...

Full description

Bibliographic Details
Main Authors: Liang Chen, Yuting Liu, Zheyu Wang, Leiyang Zhang, Yi Xu, Yinan Li, Lan Zhang, Guiming Wang, Shuofei Yang, Guanhua Xue
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00986-2