STUDY OF THE INFLUENCE OF L-NORVALINE, ROSUVASTATIN AND THEIR COMBINATION ON THE LEVEL OF MICROCIRCULATION IN BONE TISSUE IN EXPERIMENTAL OSTEOPOROSIS AND FRACTURES ON ITS BACKGROUND

The experiment was carried out in female white Wistar rats to investigate the effect of L-norvaline, rosuvastatin and their combination on parameters of blood supply to the bone tissue on models of experimental osteoporosis and osteoporotic fractures. It was found that the studied drugs prevent redu...

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Bibliographic Details
Main Authors: Samuel Densingh, Oleg Gudyrev, Alexander Faitelson, Aleksandr Stepchenko, Alexandr Dolzhikov, Sergej Povetkin
Format: Article
Language:English
Published: Belgorod National Research University 2016-03-01
Series:Research Results in Pharmacology
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Online Access:https://rrpharmacology.pensoft.net/article/31035/download/pdf/
Description
Summary:The experiment was carried out in female white Wistar rats to investigate the effect of L-norvaline, rosuvastatin and their combination on parameters of blood supply to the bone tissue on models of experimental osteoporosis and osteoporotic fractures. It was found that the studied drugs prevent reduction of microcirculation in osteoporotic bone tissue as well as in callus tissue of experimental osteoporotic fractures and it positively influences the course of reparative regeneration of bone tissue.
ISSN:2658-381X