Evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loop
Abstract Objective This study aimed to investigate the value of left ventricular (LV) press-strain loop (PSL) in evaluating global and regional myocardial work (MW) in hypertrophic cardiomyopathy (HCM) patients. Methods A total of 30 HCM patients with interventricular septum hypertrophy (HCM group)...
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| Format: | Article |
| Language: | English |
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BMC
2023-09-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | https://doi.org/10.1186/s12872-023-03519-x |
| _version_ | 1797578230149939200 |
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| author | Chengwei Xiao Xuebing Zhao Lijuan Sun Fang Zhang |
| author_facet | Chengwei Xiao Xuebing Zhao Lijuan Sun Fang Zhang |
| author_sort | Chengwei Xiao |
| collection | DOAJ |
| description | Abstract Objective This study aimed to investigate the value of left ventricular (LV) press-strain loop (PSL) in evaluating global and regional myocardial work (MW) in hypertrophic cardiomyopathy (HCM) patients. Methods A total of 30 HCM patients with interventricular septum hypertrophy (HCM group) and 35 healthy subjects (control group) were selected from First Hospital of Qinhuangdao. The general clinical data and conventional ultrasound parameters of two groups were acquired. The MW parameters were analyzed using LV PSL. The regional MW parameters in the HCM group were compared between ventricular septum and the free walls of left ventricle. Results The epicardial adipose tissue thickness of the HCM group was significantly greater than that of the control group (P < 0.05). Global work efficiency was significantly reduced, while global wasted work was increased in patients with HCM compared with controls (all P < 0.05). The HCM group was compared in the group, to be specific, in the HCM group, the work index, the work efficiency, and the longitudinal strain on the interventricular septum were lower than those on the free wall (all P < 0.05). Conclusion PSL is more effective than LVEF in assessing left ventricular systolic function in HCM and is able to quantify regional myocardial work in the ventricular septum in HCM patients with preserved LVEF, suggesting a novel idea for clinical diagnosis and assessment. |
| first_indexed | 2024-03-10T22:20:02Z |
| format | Article |
| id | doaj.art-1d884b10cdfc4395ba5a7f8877c8b799 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-03-10T22:20:02Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-1d884b10cdfc4395ba5a7f8877c8b7992023-11-19T12:18:40ZengBMCBMC Cardiovascular Disorders1471-22612023-09-012311910.1186/s12872-023-03519-xEvaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loopChengwei Xiao0Xuebing Zhao1Lijuan Sun2Fang Zhang3Hebei Medical UniversityHebei Medical UniversityDepartment of Ultrasound, First Hospital of QinhuangdaoDepartment of Ultrasound, First Hospital of QinhuangdaoAbstract Objective This study aimed to investigate the value of left ventricular (LV) press-strain loop (PSL) in evaluating global and regional myocardial work (MW) in hypertrophic cardiomyopathy (HCM) patients. Methods A total of 30 HCM patients with interventricular septum hypertrophy (HCM group) and 35 healthy subjects (control group) were selected from First Hospital of Qinhuangdao. The general clinical data and conventional ultrasound parameters of two groups were acquired. The MW parameters were analyzed using LV PSL. The regional MW parameters in the HCM group were compared between ventricular septum and the free walls of left ventricle. Results The epicardial adipose tissue thickness of the HCM group was significantly greater than that of the control group (P < 0.05). Global work efficiency was significantly reduced, while global wasted work was increased in patients with HCM compared with controls (all P < 0.05). The HCM group was compared in the group, to be specific, in the HCM group, the work index, the work efficiency, and the longitudinal strain on the interventricular septum were lower than those on the free wall (all P < 0.05). Conclusion PSL is more effective than LVEF in assessing left ventricular systolic function in HCM and is able to quantify regional myocardial work in the ventricular septum in HCM patients with preserved LVEF, suggesting a novel idea for clinical diagnosis and assessment.https://doi.org/10.1186/s12872-023-03519-xHypertrophic cardiomyopathyLeft ventriclePressure-strain loopEchocardiographyMyocardial work |
| spellingShingle | Chengwei Xiao Xuebing Zhao Lijuan Sun Fang Zhang Evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loop BMC Cardiovascular Disorders Hypertrophic cardiomyopathy Left ventricle Pressure-strain loop Echocardiography Myocardial work |
| title | Evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loop |
| title_full | Evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loop |
| title_fullStr | Evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loop |
| title_full_unstemmed | Evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loop |
| title_short | Evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure-strain loop |
| title_sort | evaluation of global and regional myocardial work in hypertrophic cardiomyopathy patients by left ventricular pressure strain loop |
| topic | Hypertrophic cardiomyopathy Left ventricle Pressure-strain loop Echocardiography Myocardial work |
| url | https://doi.org/10.1186/s12872-023-03519-x |
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