Cell Rearrangement and Oxidant/Antioxidant Imbalance in Huntington’s Disease

Cell Rearrangement and Oxidant/Antioxidant Imbalance in Huntington’s Disease

Huntington’s Disease (HD) is a hereditary neurodegenerative disorder caused by the expansion of a CAG triplet repeat in the <i>HTT</i> gene, resulting in the production of an aberrant huntingtin (Htt) protein. The mutant protein accumulation is responsible for neuronal dysfunction and ce...

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Bibliographic Details
Main Authors: Francesco D’Egidio, Vanessa Castelli, Annamaria Cimini, Michele d’Angelo
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antioxidants
Subjects:
neurodegeneration
oxidative stress
diet
vitamins
mitochondria
huntingtin
Online Access:https://www.mdpi.com/2076-3921/12/3/571

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