Association of Weight Gain Rate in Second and Third Trimesters with Pregnancy Complications and Delivery Outcomes in Women with Gestational Diabetes Mellitus
Background The total gestational weight gain is closely related to the gestational week at delivery. Choosing the gestational weight gain rate (GWGR) as a indicator can reduce the interference of gestational week on the results. Currently, available recommendations regarding GWGR are controversial....
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| Format: | Article |
| Language: | zho |
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Chinese General Practice Publishing House Co., Ltd
2022-10-01
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| Series: | Zhongguo quanke yixue |
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| Online Access: | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220410.pdf |
| _version_ | 1797216949271265280 |
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| author | Wen HUA, Lijun ZHANG, Sha LU, Jiahui XU, Nisile Kakongoma, Wensheng HU |
| author_facet | Wen HUA, Lijun ZHANG, Sha LU, Jiahui XU, Nisile Kakongoma, Wensheng HU |
| author_sort | Wen HUA, Lijun ZHANG, Sha LU, Jiahui XU, Nisile Kakongoma, Wensheng HU |
| collection | DOAJ |
| description | Background The total gestational weight gain is closely related to the gestational week at delivery. Choosing the gestational weight gain rate (GWGR) as a indicator can reduce the interference of gestational week on the results. Currently, available recommendations regarding GWGR are controversial. Few studies have explored the correlation between GWGR in second and third trimesters and delivery outcomes in women with gestational diabetes mellitus (GDM) . Objective To investigate the association of GWGR in second and third trimesters with pregnancy complications and delivery outcomes in women with GDM. Methods A total of 370 women with GDM were selected, who had an experience of undergoing delivery in Hangzhou Women's Hospital from March to December 2018, and were included in the Hangzhou Maternal and Offspring Health Cohort Study (clinical trial registration number: ChiCTR1900026149) . According to GWGR in second and third trimesters recommended by the Weight Monitoring and Evaluation during Pregnancy Period of Chinese Women published by the Chinese Nutrition Society in 2021, the subjects were divided into insufficient GWGR group (n=115) , normal GWGR group (n=152) and excessive GWGR group (n=103) . We analyzed the incidence of pregnancy complications and delivery outcomes of the three groups. Results Logistic regression analysis demonstrated that excessive GWGR in second and third trimesters was associated with an increased risk of hypertensive disorders of pregnancy〔OR=2.661, 95%CI (1.291, 9.460) 〕, gestational hypothyroidism〔OR=2.288, 95%CI (1.090, 4.805) 〕, gestational hyperlipidemia〔OR=2.085, 95%CI (1.656, 6.630) 〕 and macrosomia〔OR=4.591, 95%CI (1.238, 17.031) 〕 (P<0.05) , and a decreased risk of preterm neonate〔OR=0.117, 95%CI (0.014, 0.959) 〕 (P<0.05) . Conclusion Abnormal weight gain in pregnant women is common. Excessive GWGR in second and third trimesters may increase the risk of hypertensive disorders of pregnancy, gestational hypothyroidism, hyperlipidemia and macrosomia, and decrease the risk of preterm neonate in women with GDM. |
| first_indexed | 2024-04-24T11:54:05Z |
| format | Article |
| id | doaj.art-1d8ab96c172145dbacd56ddd0b4a4195 |
| institution | Directory Open Access Journal |
| issn | 1007-9572 |
| language | zho |
| last_indexed | 2024-04-24T11:54:05Z |
| publishDate | 2022-10-01 |
| publisher | Chinese General Practice Publishing House Co., Ltd |
| record_format | Article |
| series | Zhongguo quanke yixue |
| spelling | doaj.art-1d8ab96c172145dbacd56ddd0b4a41952024-04-09T06:05:14ZzhoChinese General Practice Publishing House Co., LtdZhongguo quanke yixue1007-95722022-10-0125293621362610.12114/j.issn.1007-9572.2022.0410Association of Weight Gain Rate in Second and Third Trimesters with Pregnancy Complications and Delivery Outcomes in Women with Gestational Diabetes MellitusWen HUA, Lijun ZHANG, Sha LU, Jiahui XU, Nisile Kakongoma, Wensheng HU01. The Fourth Clinical School of Zhejiang Chinese Medicine University, Hangzhou 310053, China;2. School of Public Health, Hangzhou Normal University Division of Health Sciences, Hangzhou 311121, China;3. Hangzhou Women's Hospital, Hangzhou 310008, ChinaBackground The total gestational weight gain is closely related to the gestational week at delivery. Choosing the gestational weight gain rate (GWGR) as a indicator can reduce the interference of gestational week on the results. Currently, available recommendations regarding GWGR are controversial. Few studies have explored the correlation between GWGR in second and third trimesters and delivery outcomes in women with gestational diabetes mellitus (GDM) . Objective To investigate the association of GWGR in second and third trimesters with pregnancy complications and delivery outcomes in women with GDM. Methods A total of 370 women with GDM were selected, who had an experience of undergoing delivery in Hangzhou Women's Hospital from March to December 2018, and were included in the Hangzhou Maternal and Offspring Health Cohort Study (clinical trial registration number: ChiCTR1900026149) . According to GWGR in second and third trimesters recommended by the Weight Monitoring and Evaluation during Pregnancy Period of Chinese Women published by the Chinese Nutrition Society in 2021, the subjects were divided into insufficient GWGR group (n=115) , normal GWGR group (n=152) and excessive GWGR group (n=103) . We analyzed the incidence of pregnancy complications and delivery outcomes of the three groups. Results Logistic regression analysis demonstrated that excessive GWGR in second and third trimesters was associated with an increased risk of hypertensive disorders of pregnancy〔OR=2.661, 95%CI (1.291, 9.460) 〕, gestational hypothyroidism〔OR=2.288, 95%CI (1.090, 4.805) 〕, gestational hyperlipidemia〔OR=2.085, 95%CI (1.656, 6.630) 〕 and macrosomia〔OR=4.591, 95%CI (1.238, 17.031) 〕 (P<0.05) , and a decreased risk of preterm neonate〔OR=0.117, 95%CI (0.014, 0.959) 〕 (P<0.05) . Conclusion Abnormal weight gain in pregnant women is common. Excessive GWGR in second and third trimesters may increase the risk of hypertensive disorders of pregnancy, gestational hypothyroidism, hyperlipidemia and macrosomia, and decrease the risk of preterm neonate in women with GDM.https://www.chinagp.net/fileup/1007-9572/PDF/zx20220410.pdfdiabetes, gestational|gestational weight gain rate in the second and third trimesters|pregnancy complications|pregnancy outcomes|cohort studies |
| spellingShingle | Wen HUA, Lijun ZHANG, Sha LU, Jiahui XU, Nisile Kakongoma, Wensheng HU Association of Weight Gain Rate in Second and Third Trimesters with Pregnancy Complications and Delivery Outcomes in Women with Gestational Diabetes Mellitus Zhongguo quanke yixue diabetes, gestational|gestational weight gain rate in the second and third trimesters|pregnancy complications|pregnancy outcomes|cohort studies |
| title | Association of Weight Gain Rate in Second and Third Trimesters with Pregnancy Complications and Delivery Outcomes in Women with Gestational Diabetes Mellitus |
| title_full | Association of Weight Gain Rate in Second and Third Trimesters with Pregnancy Complications and Delivery Outcomes in Women with Gestational Diabetes Mellitus |
| title_fullStr | Association of Weight Gain Rate in Second and Third Trimesters with Pregnancy Complications and Delivery Outcomes in Women with Gestational Diabetes Mellitus |
| title_full_unstemmed | Association of Weight Gain Rate in Second and Third Trimesters with Pregnancy Complications and Delivery Outcomes in Women with Gestational Diabetes Mellitus |
| title_short | Association of Weight Gain Rate in Second and Third Trimesters with Pregnancy Complications and Delivery Outcomes in Women with Gestational Diabetes Mellitus |
| title_sort | association of weight gain rate in second and third trimesters with pregnancy complications and delivery outcomes in women with gestational diabetes mellitus |
| topic | diabetes, gestational|gestational weight gain rate in the second and third trimesters|pregnancy complications|pregnancy outcomes|cohort studies |
| url | https://www.chinagp.net/fileup/1007-9572/PDF/zx20220410.pdf |
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