Heterologous Prime-Boost Vaccination Enhances TsPmy’s Protective Immunity against Trichinella spiralis Infection in a Murine Model

Heterologous Prime-Boost Vaccination Enhances TsPmy’s Protective Immunity against Trichinella spiralis Infection in a Murine Model

TsPmy is a paramyosin expressed by parasitic Trichinella spiralis and confers a protective immunity when its recombinant protein or DNA was used as an immunogen. To improve its immunogenicity and vaccine efficacy, we conducted a heterologous prime-boost strategy by orally delivering one dose of TsPm...

Full description

Bibliographic Details
Main Authors: Lei Wang, Ximeng Sun, Jingjing Huang, Bin Zhan, Xinping Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Microbiology
Subjects:
Trichinella spiralis
vaccine
prime-boost
mucosal immunity
Salmonella typhimurium
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01394/full

Similar Items

Similar Items