Surface Enhanced Raman Scattering (SERS): From Fundamental Mechanism to Bio-Analytics Tools

This review discusses the surface-enhanced Raman scattering (SERS) with efficiencies enhanced by as much as 1014-1015 fold as well as a SERS cross section on the order of 10-17-10-16 cm2/molecule. Despite the existing controversy on the origin of the enhancement, SERS effect offers new opportunities...

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Main Authors: Xiao Zhi, Li Lin, Di Chen
Format: Article
Language:English
Published: Tsinghua University Press 2016-12-01
Series:Nano Biomedicine and Engineering
Subjects:
Online Access:https://www.sciopen.com/article/10.5101/nbe.v8i4.p297-305
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author Xiao Zhi
Li Lin
Di Chen
author_facet Xiao Zhi
Li Lin
Di Chen
author_sort Xiao Zhi
collection DOAJ
description This review discusses the surface-enhanced Raman scattering (SERS) with efficiencies enhanced by as much as 1014-1015 fold as well as a SERS cross section on the order of 10-17-10-16 cm2/molecule. Despite the existing controversy on the origin of the enhancement, SERS effect offers new opportunities for spectroscopic detection of single molecules near or on the surface of metallic nanoparticles. There has been a considerable amount of research on explanation of the enhancement mechanism and on developing SERS labels as bio-analytics tools for either molecular multiplexed detection or bio-imaging at different levels.
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spelling doaj.art-1d942ea67b174174a76c616dfb6641d02023-09-26T10:54:54ZengTsinghua University PressNano Biomedicine and Engineering2150-55782016-12-018429730510.5101/nbe.v8i4.p297-305Surface Enhanced Raman Scattering (SERS): From Fundamental Mechanism to Bio-Analytics ToolsXiao Zhi0Li Lin1Di Chen2Institute of Nano Biomedicine and Engineering, Shanghai Engineering Center for Intelligent Diagnosis and Treatment Instrument, Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P. R. ChinaInstitute of Nano Biomedicine and Engineering, Shanghai Engineering Center for Intelligent Diagnosis and Treatment Instrument, Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P. R. ChinaInstitute of Nano Biomedicine and Engineering, Shanghai Engineering Center for Intelligent Diagnosis and Treatment Instrument, Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P. R. ChinaThis review discusses the surface-enhanced Raman scattering (SERS) with efficiencies enhanced by as much as 1014-1015 fold as well as a SERS cross section on the order of 10-17-10-16 cm2/molecule. Despite the existing controversy on the origin of the enhancement, SERS effect offers new opportunities for spectroscopic detection of single molecules near or on the surface of metallic nanoparticles. There has been a considerable amount of research on explanation of the enhancement mechanism and on developing SERS labels as bio-analytics tools for either molecular multiplexed detection or bio-imaging at different levels.https://www.sciopen.com/article/10.5101/nbe.v8i4.p297-305ramansersmachanismbio-analytics
spellingShingle Xiao Zhi
Li Lin
Di Chen
Surface Enhanced Raman Scattering (SERS): From Fundamental Mechanism to Bio-Analytics Tools
Nano Biomedicine and Engineering
raman
sers
machanism
bio-analytics
title Surface Enhanced Raman Scattering (SERS): From Fundamental Mechanism to Bio-Analytics Tools
title_full Surface Enhanced Raman Scattering (SERS): From Fundamental Mechanism to Bio-Analytics Tools
title_fullStr Surface Enhanced Raman Scattering (SERS): From Fundamental Mechanism to Bio-Analytics Tools
title_full_unstemmed Surface Enhanced Raman Scattering (SERS): From Fundamental Mechanism to Bio-Analytics Tools
title_short Surface Enhanced Raman Scattering (SERS): From Fundamental Mechanism to Bio-Analytics Tools
title_sort surface enhanced raman scattering sers from fundamental mechanism to bio analytics tools
topic raman
sers
machanism
bio-analytics
url https://www.sciopen.com/article/10.5101/nbe.v8i4.p297-305
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AT lilin surfaceenhancedramanscatteringsersfromfundamentalmechanismtobioanalyticstools
AT dichen surfaceenhancedramanscatteringsersfromfundamentalmechanismtobioanalyticstools