Clausenlanins A and B, Two Leucine-Rich Cyclic Nonapeptides from Clausena lansium
Abstract Two new cyclic nonapeptides, named clausenlanins A (1) and B (2), were isolated from the roots and rhizomes of Clausena lansium. Their structures were elucidated as cyclo-(Gly1-l-Leu2-l-Ile3-l-Leu4-l-Leu5-l-Leu6-l-Leu7-l-Leu8-l-Leu9) (1) and cyclo-(Gly1-l-Leu2-l-Val3-l-Leu4-l-Leu5-l-Leu6-l-...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2017-06-01
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| Series: | Natural Products and Bioprospecting |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1007/s13659-017-0133-y |
| Summary: | Abstract Two new cyclic nonapeptides, named clausenlanins A (1) and B (2), were isolated from the roots and rhizomes of Clausena lansium. Their structures were elucidated as cyclo-(Gly1-l-Leu2-l-Ile3-l-Leu4-l-Leu5-l-Leu6-l-Leu7-l-Leu8-l-Leu9) (1) and cyclo-(Gly1-l-Leu2-l-Val3-l-Leu4-l-Leu5-l-Leu6-l-Leu7-l-Leu8-l-Leu9) (2) respectively on the basis of extensive spectroscopic analysis, particularly 2D NMR spectra taken at the temperature of 338 or 303 K and MS. Graphical Abstract |
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| ISSN: | 2192-2195 2192-2209 |