Changes in coagulation in patients with ischemic stroke

The aim of the study was to assess the dynamics of coagulation indices in patients with acute ischemic stroke. The study revealed that atherothrombotic type of stroke prevailed in patients (66.8%), cerebrovascular thrombosis (20.0%) was less common, cardioembolic type was noted in 22.2% of cases. Th...

Full description

Bibliographic Details
Main Authors: Denys Khramtsov, Marina Vikarenko, Galina Kozlova, Yuriy Vorokhta
Format: Article
Language:English
Published: Kazimierz Wielki University 2017-04-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/24054
_version_ 1818141007480356864
author Denys Khramtsov
Marina Vikarenko
Galina Kozlova
Yuriy Vorokhta
author_facet Denys Khramtsov
Marina Vikarenko
Galina Kozlova
Yuriy Vorokhta
author_sort Denys Khramtsov
collection DOAJ
description The aim of the study was to assess the dynamics of coagulation indices in patients with acute ischemic stroke. The study revealed that atherothrombotic type of stroke prevailed in patients (66.8%), cerebrovascular thrombosis (20.0%) was less common, cardioembolic type was noted in 22.2% of cases. The average inpatient days were 18.11.1. The coagulogram patterns demonstrated hypercoagulation on the 1st  day after stroke onset, on the 3rd  hypercoagulation persisted,. By the seventh day, normalization of mean values of screening parameters of hemostasis was established, and by the 14th day of stroke there was a tendency to hypocoagulation. In patients with hemorrhagic transformation, the values of ICC and ICP parameters increased by day 7, in addition, there was an increase in the content of fibrinogen. A visual display of the blood coagulation activity allows for more accurate selection of anticoagulation therapy, prevention of hemorrhagic transformation.
first_indexed 2024-12-11T10:53:02Z
format Article
id doaj.art-1d9bddee4fe94c41833e3663f447ee97
institution Directory Open Access Journal
issn 2391-8306
language English
last_indexed 2024-12-11T10:53:02Z
publishDate 2017-04-01
publisher Kazimierz Wielki University
record_format Article
series Journal of Education, Health and Sport
spelling doaj.art-1d9bddee4fe94c41833e3663f447ee972022-12-22T01:10:12ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-04-0174Changes in coagulation in patients with ischemic strokeDenys Khramtsov0Marina Vikarenko1Galina Kozlova2Yuriy Vorokhta3Odessa National Medical UniversityOdessa National Medical UniversityOdessa National Medical UniversityOdessa National Medical UniversityThe aim of the study was to assess the dynamics of coagulation indices in patients with acute ischemic stroke. The study revealed that atherothrombotic type of stroke prevailed in patients (66.8%), cerebrovascular thrombosis (20.0%) was less common, cardioembolic type was noted in 22.2% of cases. The average inpatient days were 18.11.1. The coagulogram patterns demonstrated hypercoagulation on the 1st  day after stroke onset, on the 3rd  hypercoagulation persisted,. By the seventh day, normalization of mean values of screening parameters of hemostasis was established, and by the 14th day of stroke there was a tendency to hypocoagulation. In patients with hemorrhagic transformation, the values of ICC and ICP parameters increased by day 7, in addition, there was an increase in the content of fibrinogen. A visual display of the blood coagulation activity allows for more accurate selection of anticoagulation therapy, prevention of hemorrhagic transformation.https://apcz.umk.pl/JEHS/article/view/24054strokecoagulationdiagnosis
spellingShingle Denys Khramtsov
Marina Vikarenko
Galina Kozlova
Yuriy Vorokhta
Changes in coagulation in patients with ischemic stroke
Journal of Education, Health and Sport
stroke
coagulation
diagnosis
title Changes in coagulation in patients with ischemic stroke
title_full Changes in coagulation in patients with ischemic stroke
title_fullStr Changes in coagulation in patients with ischemic stroke
title_full_unstemmed Changes in coagulation in patients with ischemic stroke
title_short Changes in coagulation in patients with ischemic stroke
title_sort changes in coagulation in patients with ischemic stroke
topic stroke
coagulation
diagnosis
url https://apcz.umk.pl/JEHS/article/view/24054
work_keys_str_mv AT denyskhramtsov changesincoagulationinpatientswithischemicstroke
AT marinavikarenko changesincoagulationinpatientswithischemicstroke
AT galinakozlova changesincoagulationinpatientswithischemicstroke
AT yuriyvorokhta changesincoagulationinpatientswithischemicstroke