Shifting from tuberculosis control to elimination: Where are we? What are the variables and limitations? Is it achievable?
Tuberculosis (TB) is a priority in terms of incidence and mortality, with about 10.4 million new incident cases and 1.8 million deaths in 2015. The End-TB strategy recently launched by the World Health Organization in the context of the post-2015 agenda, aimed to achieve TB elimination, represents a...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-03-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971216316356 |
| _version_ | 1818238247950614528 |
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| author | Rosella Centis Lia D’Ambrosio Alimuddin Zumla Giovanni Battista Migliori |
| author_facet | Rosella Centis Lia D’Ambrosio Alimuddin Zumla Giovanni Battista Migliori |
| author_sort | Rosella Centis |
| collection | DOAJ |
| description | Tuberculosis (TB) is a priority in terms of incidence and mortality, with about 10.4 million new incident cases and 1.8 million deaths in 2015. The End-TB strategy recently launched by the World Health Organization in the context of the post-2015 agenda, aimed to achieve TB elimination, represents an evolution of the previous historical strategies originally aimed to achieve TB control. Globally, the current decline in TB incidence is rather slow at approximately 1,5% per year to reach the TB pre-elimination phase by 2035 (A more aggressive approach based on diagnosis and treatment of latently infected individuals has been proposed in the context of TB elimination to ensure future generations free of TB. We describes 4 scenarios which, combined, describe the TB epidemiology in a given setting: 1) in absence of interventions, 2) with early TB diagnosis and effective treatment, 3) with irregular TB treatment, 4) with TB co-infected by HIV not undergoing anti-retroviral treatment. To achieve TB Elimination, a more concerted action by funders and governments will be required for further investments into TB prevention, detection and treatment. |
| first_indexed | 2024-12-12T12:38:38Z |
| format | Article |
| id | doaj.art-1d9cb1a783d343c797182b214541c9cf |
| institution | Directory Open Access Journal |
| issn | 1201-9712 1878-3511 |
| language | English |
| last_indexed | 2024-12-12T12:38:38Z |
| publishDate | 2017-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-1d9cb1a783d343c797182b214541c9cf2022-12-22T00:24:15ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112017-03-0156C303310.1016/j.ijid.2016.11.416Shifting from tuberculosis control to elimination: Where are we? What are the variables and limitations? Is it achievable?Rosella Centis0Lia D’Ambrosio1Alimuddin Zumla2Giovanni Battista Migliori3World Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Maugeri Institute, IRCCS, Via Roncaccio 16, 21049, Tradate, ItalyWorld Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Maugeri Institute, IRCCS, Via Roncaccio 16, 21049, Tradate, ItalyCentre for Clinical Microbiology, Division of Infection and Immunity, University College London and NIHR Biomedical Research Centre, UCL Hospitals NHS Foundation Trust, London, UKWorld Health Organization Collaborating Centre for Tuberculosis and Lung Diseases, Maugeri Institute, IRCCS, Via Roncaccio 16, 21049, Tradate, ItalyTuberculosis (TB) is a priority in terms of incidence and mortality, with about 10.4 million new incident cases and 1.8 million deaths in 2015. The End-TB strategy recently launched by the World Health Organization in the context of the post-2015 agenda, aimed to achieve TB elimination, represents an evolution of the previous historical strategies originally aimed to achieve TB control. Globally, the current decline in TB incidence is rather slow at approximately 1,5% per year to reach the TB pre-elimination phase by 2035 (A more aggressive approach based on diagnosis and treatment of latently infected individuals has been proposed in the context of TB elimination to ensure future generations free of TB. We describes 4 scenarios which, combined, describe the TB epidemiology in a given setting: 1) in absence of interventions, 2) with early TB diagnosis and effective treatment, 3) with irregular TB treatment, 4) with TB co-infected by HIV not undergoing anti-retroviral treatment. To achieve TB Elimination, a more concerted action by funders and governments will be required for further investments into TB prevention, detection and treatment.http://www.sciencedirect.com/science/article/pii/S1201971216316356TuberculosisEliminationMDR-TBLTBIStrategy |
| spellingShingle | Rosella Centis Lia D’Ambrosio Alimuddin Zumla Giovanni Battista Migliori Shifting from tuberculosis control to elimination: Where are we? What are the variables and limitations? Is it achievable? International Journal of Infectious Diseases Tuberculosis Elimination MDR-TB LTBI Strategy |
| title | Shifting from tuberculosis control to elimination: Where are we? What are the variables and limitations? Is it achievable? |
| title_full | Shifting from tuberculosis control to elimination: Where are we? What are the variables and limitations? Is it achievable? |
| title_fullStr | Shifting from tuberculosis control to elimination: Where are we? What are the variables and limitations? Is it achievable? |
| title_full_unstemmed | Shifting from tuberculosis control to elimination: Where are we? What are the variables and limitations? Is it achievable? |
| title_short | Shifting from tuberculosis control to elimination: Where are we? What are the variables and limitations? Is it achievable? |
| title_sort | shifting from tuberculosis control to elimination where are we what are the variables and limitations is it achievable |
| topic | Tuberculosis Elimination MDR-TB LTBI Strategy |
| url | http://www.sciencedirect.com/science/article/pii/S1201971216316356 |
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