A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice

Abstract Opioid use disorders (OUD) and opioid-related fatal overdoses are a public health concern in the United States. Approximately 100,000 fatal opioid-related overdoses occurred annually from mid-2020 to the present, the majority of which involved fentanyl or fentanyl analogs. Vaccines have bee...

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Bibliographic Details
Main Authors: Shannon M. Miller, Bethany Crouse, Linda Hicks, Hardik Amin, Shelby Cole, Helene G. Bazin, David J. Burkhart, Marco Pravetoni, Jay T. Evans
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00694-y

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