A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice
Abstract Opioid use disorders (OUD) and opioid-related fatal overdoses are a public health concern in the United States. Approximately 100,000 fatal opioid-related overdoses occurred annually from mid-2020 to the present, the majority of which involved fentanyl or fentanyl analogs. Vaccines have bee...
Main Authors: | Shannon M. Miller, Bethany Crouse, Linda Hicks, Hardik Amin, Shelby Cole, Helene G. Bazin, David J. Burkhart, Marco Pravetoni, Jay T. Evans |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-023-00694-y |
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