Clinical validation of an evidence-based method to adjust Pancreatic Enzyme Replacement Therapy through a prospective interventional study in paediatric patients with Cystic Fibrosis.

Clinical validation of an evidence-based method to adjust Pancreatic Enzyme Replacement Therapy through a prospective interventional study in paediatric patients with Cystic Fibrosis.

<h4>Background</h4>A method to adjust Pancreatic Enzyme Replacement Therapy in Cystic Fibrosis is not currently available.<h4>Objectives</h4>To assess the in vivo efficacy of a method to adjust the dose of enzymatic supplement in CF extrapolated from previous in vitro digesti...

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Main Authors: Joaquim Calvo-Lerma, Jessie Hulst, Mieke Boon, Carla Colombo, Etna Masip, Mar Ruperto, Victoria Fornés-Ferrer, Els van der Wiel, Ine Claes, Maria Garriga, Maria Roca, Paula Crespo-Escobar, Anna Bulfamante, Sandra Woodcock, Sandra Martínez-Barona, Ana Andrés, Kris de Boeck, Carmen Ribes-Koninckx, MyCyFAPP project
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213216

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