Assessment of pain management after orthognathic surgery by the administration of montelukast: An original research

Introduction: Opioid may cause undue risk after surgical procedures like orthognathic surgeries. The present study was aimed to determine how the preoperative administration of oral montelukast affected the degree of postoperative discomfort following bimaxillary orthognathic surgery (BOS). Methodol...

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Main Authors: G Jeevan Kumar, Samir Mansuri, Sarin A Nizar, Sameera Qureshi Mohd Rehman, Abhishekh Kumar, Fawaz Abdul Hamid Baig
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=5;spage=114;epage=117;aulast=Kumar
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author G Jeevan Kumar
Samir Mansuri
Sarin A Nizar
Sameera Qureshi Mohd Rehman
Abhishekh Kumar
Fawaz Abdul Hamid Baig
author_facet G Jeevan Kumar
Samir Mansuri
Sarin A Nizar
Sameera Qureshi Mohd Rehman
Abhishekh Kumar
Fawaz Abdul Hamid Baig
author_sort G Jeevan Kumar
collection DOAJ
description Introduction: Opioid may cause undue risk after surgical procedures like orthognathic surgeries. The present study was aimed to determine how the preoperative administration of oral montelukast affected the degree of postoperative discomfort following bimaxillary orthognathic surgery (BOS). Methodology: This study included all skeletal class III subjects scheduled for BOS. The participants were split into placebo and montelukast groups at random. Every patient received a 10-mL serving of apple juice an hour prior to the surgery; however, for the intervention group, a montelukast 10 mg pill was dissolved in the juice. The same surgical team and general anesthetic guidelines were used for all procedures. The visual analog scale (VAS) was used to calculate postoperative pain at designated intervals. The significance level for the statistical analysis was determined using the Statistical Package for the Social Sciences (SPSS) version 23. Results: The control subjects had a higher level of pain at all the intervals than the intended drug test group. Also, the control group needed more analgesics than the test group. There was one observation made that the length of the surgery had an impact on the postoperative pain. Conclusion: Preoperative montelukast medication may be useful in minimizing postoperative discomfort following bimaxillary orthognathic surgery. More research is required for greater relevance.
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spelling doaj.art-1da9b8dc65bc4190bf50c4343fb46bc92023-10-30T10:31:53ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74062023-01-0115511411710.4103/jpbs.jpbs_432_22Assessment of pain management after orthognathic surgery by the administration of montelukast: An original researchG Jeevan KumarSamir MansuriSarin A NizarSameera Qureshi Mohd RehmanAbhishekh KumarFawaz Abdul Hamid BaigIntroduction: Opioid may cause undue risk after surgical procedures like orthognathic surgeries. The present study was aimed to determine how the preoperative administration of oral montelukast affected the degree of postoperative discomfort following bimaxillary orthognathic surgery (BOS). Methodology: This study included all skeletal class III subjects scheduled for BOS. The participants were split into placebo and montelukast groups at random. Every patient received a 10-mL serving of apple juice an hour prior to the surgery; however, for the intervention group, a montelukast 10 mg pill was dissolved in the juice. The same surgical team and general anesthetic guidelines were used for all procedures. The visual analog scale (VAS) was used to calculate postoperative pain at designated intervals. The significance level for the statistical analysis was determined using the Statistical Package for the Social Sciences (SPSS) version 23. Results: The control subjects had a higher level of pain at all the intervals than the intended drug test group. Also, the control group needed more analgesics than the test group. There was one observation made that the length of the surgery had an impact on the postoperative pain. Conclusion: Preoperative montelukast medication may be useful in minimizing postoperative discomfort following bimaxillary orthognathic surgery. More research is required for greater relevance.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=5;spage=114;epage=117;aulast=Kumarbimaxillary orthognathic surgerymontelukastpain
spellingShingle G Jeevan Kumar
Samir Mansuri
Sarin A Nizar
Sameera Qureshi Mohd Rehman
Abhishekh Kumar
Fawaz Abdul Hamid Baig
Assessment of pain management after orthognathic surgery by the administration of montelukast: An original research
Journal of Pharmacy and Bioallied Sciences
bimaxillary orthognathic surgery
montelukast
pain
title Assessment of pain management after orthognathic surgery by the administration of montelukast: An original research
title_full Assessment of pain management after orthognathic surgery by the administration of montelukast: An original research
title_fullStr Assessment of pain management after orthognathic surgery by the administration of montelukast: An original research
title_full_unstemmed Assessment of pain management after orthognathic surgery by the administration of montelukast: An original research
title_short Assessment of pain management after orthognathic surgery by the administration of montelukast: An original research
title_sort assessment of pain management after orthognathic surgery by the administration of montelukast an original research
topic bimaxillary orthognathic surgery
montelukast
pain
url http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2023;volume=15;issue=5;spage=114;epage=117;aulast=Kumar
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