Differential diagnosis of anemia in true and functional iron deficiency in patients with chronic diseases (malignant tumors)
Aim. To make a differential diagnosis of true and functional iron deficiency (ID) in anemia of chronic diseases (ACD). Subjects and methods. A total of 540 patients (785 investigations) and 311 healthy individuals (a control group) were examined. Among them, there were 118 cancer patients admitted f...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2016-04-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/31975/pdf |
| Summary: | Aim. To make a differential diagnosis of true and functional iron deficiency (ID) in anemia of chronic diseases (ACD). Subjects and methods. A total of 540 patients (785 investigations) and 311 healthy individuals (a control group) were examined. Among them, there were 118 cancer patients admitted for surgical treatment and 226 for chemotherapy (CT), 56 blood cancer patients, 86 with breast diseases without anemia, and 54 workers of the institute with the signs of ID. An enzyme immunoassay was used to determine the plasma levels of ferritin (FR), soluble transferrin receptor (sTFR), and endogenous erythropoietin (EPO). Results. 183 cancer patients did not receive specific treatment, 161 had different cycles of CT. In true ID, anemia was microcytic (average red blood cell size, |
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| ISSN: | 0040-3660 2309-5342 |