Chagas disease: What is known and what should be improved: a systemic review
This study consists of a broad review on what is known and what should be improved regarding knowledge of Chagas disease, not only through analysis on the main studies published on the topics discussed, but to a large extent based on experience of this subject, acquired over the past 50 years (1961-...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2012-06-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000300002&lng=en&tlng=en |
| _version_ | 1818534492767256576 |
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| author | José Rodrigues Coura José Borges-Pereira |
| author_facet | José Rodrigues Coura José Borges-Pereira |
| author_sort | José Rodrigues Coura |
| collection | DOAJ |
| description | This study consists of a broad review on what is known and what should be improved regarding knowledge of Chagas disease, not only through analysis on the main studies published on the topics discussed, but to a large extent based on experience of this subject, acquired over the past 50 years (1961-2011). Among the subjects covered, we highlight the pathogenesis and evolution of infection by Trypanosoma cruzi, drugs in use and new strategies for treating Chagas disease; the serological tests for the diagnosis and the controls of cure the infection; the regional variations in prevalence, morbidity and response to treatment of the disease; the importance of metacyclogenesis of T. cruzi in different species of triatomines and its capacity to transmit Chagas infection; the risks of adaptation of wild triatomines to human dwellings; the morbidity and need for a surveillance and control program for Chagas disease in the Amazon region and the need to prioritize initiatives for controlling Chagas disease in Latin America and Mexico and in non-endemic countries, which is today a major international dilemma. Finally, we raise the need for to create a new initiative for controlling Chagas disease in the Gran Chaco, which involves parts of Argentina, Bolivia and Paraguay. |
| first_indexed | 2024-12-11T18:12:21Z |
| format | Article |
| id | doaj.art-1dad3445fb8a47ae918de06e75f0e8a9 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-12-11T18:12:21Z |
| publishDate | 2012-06-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-1dad3445fb8a47ae918de06e75f0e8a92022-12-22T00:55:31ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492012-06-0145328629610.1590/S0037-86822012000300002S0037-86822012000300002Chagas disease: What is known and what should be improved: a systemic reviewJosé Rodrigues Coura0José Borges-Pereira1Fundação Oswaldo CruzFundação Oswaldo CruzThis study consists of a broad review on what is known and what should be improved regarding knowledge of Chagas disease, not only through analysis on the main studies published on the topics discussed, but to a large extent based on experience of this subject, acquired over the past 50 years (1961-2011). Among the subjects covered, we highlight the pathogenesis and evolution of infection by Trypanosoma cruzi, drugs in use and new strategies for treating Chagas disease; the serological tests for the diagnosis and the controls of cure the infection; the regional variations in prevalence, morbidity and response to treatment of the disease; the importance of metacyclogenesis of T. cruzi in different species of triatomines and its capacity to transmit Chagas infection; the risks of adaptation of wild triatomines to human dwellings; the morbidity and need for a surveillance and control program for Chagas disease in the Amazon region and the need to prioritize initiatives for controlling Chagas disease in Latin America and Mexico and in non-endemic countries, which is today a major international dilemma. Finally, we raise the need for to create a new initiative for controlling Chagas disease in the Gran Chaco, which involves parts of Argentina, Bolivia and Paraguay.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000300002&lng=en&tlng=enDoença de ChagasPadrão evolutivoInteração Trypanosoma cruzi-vetoresNovas estratégias para o tratamentoVigilância e controle |
| spellingShingle | José Rodrigues Coura José Borges-Pereira Chagas disease: What is known and what should be improved: a systemic review Revista da Sociedade Brasileira de Medicina Tropical Doença de Chagas Padrão evolutivo Interação Trypanosoma cruzi-vetores Novas estratégias para o tratamento Vigilância e controle |
| title | Chagas disease: What is known and what should be improved: a systemic review |
| title_full | Chagas disease: What is known and what should be improved: a systemic review |
| title_fullStr | Chagas disease: What is known and what should be improved: a systemic review |
| title_full_unstemmed | Chagas disease: What is known and what should be improved: a systemic review |
| title_short | Chagas disease: What is known and what should be improved: a systemic review |
| title_sort | chagas disease what is known and what should be improved a systemic review |
| topic | Doença de Chagas Padrão evolutivo Interação Trypanosoma cruzi-vetores Novas estratégias para o tratamento Vigilância e controle |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000300002&lng=en&tlng=en |
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