How to measure retinal microperfusion in patients with arterial hypertension
Purpose Assessment and monitoring of changes in microcirculatory perfusion, perfusion dynamic, vessel structure and oxygenation is crucial in management of arterial hypertension. Constant search for non-invasive methods has led the clinical focus towards the vasculature of the retina, which offers a...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | Blood Pressure |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/08037051.2020.1823816 |
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| author | Urszula Szulc Edyta Dąbrowska Janusz Pieczyński Paweł Białkowski Krzysztof Narkiewicz Roland E. Schmieder Joanna Harazny |
| author_facet | Urszula Szulc Edyta Dąbrowska Janusz Pieczyński Paweł Białkowski Krzysztof Narkiewicz Roland E. Schmieder Joanna Harazny |
| author_sort | Urszula Szulc |
| collection | DOAJ |
| description | Purpose Assessment and monitoring of changes in microcirculatory perfusion, perfusion dynamic, vessel structure and oxygenation is crucial in management of arterial hypertension. Constant search for non-invasive methods has led the clinical focus towards the vasculature of the retina, which offers a large opportunity to detect the early phase of the functional and structural changes in the arterial hypertension and can reflect changes in brain vasculature. We review all the available methods of retinal microcirculation measurements including angiography, oximetry, retinal vasculature assessment software, Optical Coherence Tomography Angiography, Adaptive Optics and Scanning Laser Doppler Flowmetry and their application in clinical research. Materials and methods To further analyse the applicability of described methods in hypertension research we performed a systematic search of the PubMed electronic database (April 2020). In our analysis, we included 111 articles in which at least one of described methods was used for assessment of microcirculation of the retina in hypertensive individuals. Results Up to this point, the methods most commonly published in studies of retinal microcirculation in arterial hypertension were Scanning Laser Doppler Flowmetry followed shortly by Optical Coherence Tomography Angiography and retinal vasculature assessment software. Conclusions While none of described methods enables the simultaneous measurement of all microcirculatory parameters, certain techniques are widely used in arterial hypertension research, while others gain popularity in screening. |
| first_indexed | 2024-03-12T00:38:52Z |
| format | Article |
| id | doaj.art-1db07938c9fb49569977066ef1932758 |
| institution | Directory Open Access Journal |
| issn | 0803-7051 1651-1999 |
| language | English |
| last_indexed | 2024-03-12T00:38:52Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Blood Pressure |
| spelling | doaj.art-1db07938c9fb49569977066ef19327582023-09-15T08:45:23ZengTaylor & Francis GroupBlood Pressure0803-70511651-19992021-01-0130141910.1080/08037051.2020.18238161823816How to measure retinal microperfusion in patients with arterial hypertensionUrszula Szulc0Edyta Dąbrowska1Janusz Pieczyński2Paweł Białkowski3Krzysztof Narkiewicz4Roland E. Schmieder5Joanna Harazny6Department of Human Physiology and Pathophysiology, University Warmia and MazuryDepartment of Hypertension and Diabetology, Faculty of Medicine, Medical University of GdańskDepartment of Ophthalmology, University Warmia and MazuryDepartment of Ophthalmology, Provincial Specialist HospitalDepartment of Hypertension and Diabetology, Faculty of Medicine, Medical University of GdańskClinical Research Center, Department of Nephrology and Hypertensiology, University Erlangen-NurembergDepartment of Human Physiology and Pathophysiology, University Warmia and MazuryPurpose Assessment and monitoring of changes in microcirculatory perfusion, perfusion dynamic, vessel structure and oxygenation is crucial in management of arterial hypertension. Constant search for non-invasive methods has led the clinical focus towards the vasculature of the retina, which offers a large opportunity to detect the early phase of the functional and structural changes in the arterial hypertension and can reflect changes in brain vasculature. We review all the available methods of retinal microcirculation measurements including angiography, oximetry, retinal vasculature assessment software, Optical Coherence Tomography Angiography, Adaptive Optics and Scanning Laser Doppler Flowmetry and their application in clinical research. Materials and methods To further analyse the applicability of described methods in hypertension research we performed a systematic search of the PubMed electronic database (April 2020). In our analysis, we included 111 articles in which at least one of described methods was used for assessment of microcirculation of the retina in hypertensive individuals. Results Up to this point, the methods most commonly published in studies of retinal microcirculation in arterial hypertension were Scanning Laser Doppler Flowmetry followed shortly by Optical Coherence Tomography Angiography and retinal vasculature assessment software. Conclusions While none of described methods enables the simultaneous measurement of all microcirculatory parameters, certain techniques are widely used in arterial hypertension research, while others gain popularity in screening.http://dx.doi.org/10.1080/08037051.2020.1823816arterial hypertensionmicroperfusionretinal microvasculature |
| spellingShingle | Urszula Szulc Edyta Dąbrowska Janusz Pieczyński Paweł Białkowski Krzysztof Narkiewicz Roland E. Schmieder Joanna Harazny How to measure retinal microperfusion in patients with arterial hypertension Blood Pressure arterial hypertension microperfusion retinal microvasculature |
| title | How to measure retinal microperfusion in patients with arterial hypertension |
| title_full | How to measure retinal microperfusion in patients with arterial hypertension |
| title_fullStr | How to measure retinal microperfusion in patients with arterial hypertension |
| title_full_unstemmed | How to measure retinal microperfusion in patients with arterial hypertension |
| title_short | How to measure retinal microperfusion in patients with arterial hypertension |
| title_sort | how to measure retinal microperfusion in patients with arterial hypertension |
| topic | arterial hypertension microperfusion retinal microvasculature |
| url | http://dx.doi.org/10.1080/08037051.2020.1823816 |
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